Complement C5 - CISMeF

Preferred Label : Complement C5;

NCIt synonyms : C5; C3 and PZP-Like Alpha-2-Macroglobulin Domain-Containing Protein 4; Complement Component 5; Complement Component-5; Prepro-C5;

NCIt definition : Complement C5 (1676 aa, 188 kDa) is encoded by the human C5 gene. This protein is involved in complement-mediated immunity.;

NCIt note : Complement C5 is cleaved into the following 4 chains: Complement C5 beta chain, Complement C5 alpha chain, C5a anaphylatoxin, and Complement C5 alpha' chain. (UniProt);

Details

Origin ID

C21539;

UMLS CUI

C5441695;

Currated CISMeF NLP mapping
- Complement C5 [LOINC component]
- Complement component C5 (substance) [SNOMED CT concept]
- complement C5 [MeSH Descriptor]
- complement C5 [MeSH concept]
- complement component c5, nos [SNOMED Notion]
OMIM relation
- Complement component 5 [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Immunologic Factor [UMLS semantic type]
UMLS correspondences (same concept)
- Complement C5 [LOINC component]
- Complement component C5 (substance) [SNOMED CT concept]
- complement C5 [MeSH concept]
- complement C5 [MeSH Descriptor]
- complement component c5, nos [SNOMED Notion]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_encodes_gene_product
- C5 Gene [NCIt concept]
- Complement Component Gene [NCIt concept]
gene_product_has_biochemical_function
- Complement [NCIt concept]
gene_product_has_organism_source
- Human [NCIt concept]
gene_product_is_element_in_pathway
- Alternative Complement Pathway [NCIt concept]
- Classical Complement Pathway [NCIt concept]
- Complement Pathway [NCIt concept]
- Granulocyte Adhesion Pathway [NCIt concept]
- Lectin Induced Complement Pathway [NCIt concept]
- Local Acute Inflammatory Response Pathway [NCIt concept]
gene_product_malfunction_associated_with_disease
- C5 Deficiency [NCIt concept]
gene_product_plays_role_in_biological_process
- Chemotactic Process [NCIt concept]
- Complement Activation [NCIt concept]
- Inflammatory Response [NCIt concept]
- Stress Response Signaling [NCIt concept]
is_target
- Crovalimab [NCIt concept]
- Eculizumab [NCIt concept]
- Gefurulimab [NCIt concept]
- Pozelimab [NCIt concept]
- Ravulizumab [NCIt concept]
- Tesidolumab [NCIt concept]
- Zilucoplan [NCIt concept]

Keyword's position in hierarchy(ies) :

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