complement C5 - CISMeF

Preferred Label : complement C5;

MeSH definition : C5 plays a central role in both the classical and the alternative pathway of COMPLEMENT ACTIVATION. C5 is cleaved by C5 CONVERTASE into COMPLEMENT C5A and COMPLEMENT C5B. The smaller fragment C5a is an ANAPHYLATOXIN and mediator of inflammatory process. The major fragment C5b binds to the membrane initiating the spontaneous assembly of the late complement components, C5-C9, into the MEMBRANE ATTACK COMPLEX.;

MeSH synonym : c5, complement; complement component 5; component 5, complement; c5 complement; complement 5; complement, C5;

MeSH Hyperonym : complement C5, precursor; C5, Precursor Complement; Precursor Complement C5; Pro-C5; Pro C5; Pro-complement 5; Pro complement 5; Precursor C5; C5, Precursor;

Wikipedia link : https://en.wikipedia.org/wiki/Complement c5;

Is substance : O;

Details

Origin ID

D003182;

UMLS CUI

C0009519;

Allowable qualifiers
- administration and dosage [MeSH Qualifier]
- adverse effects [MeSH Qualifier]
- agonists [MeSH Qualifier]
- analysis [MeSH Qualifier]
- antagonists and inhibitors [MeSH Qualifier]
- biosynthesis [MeSH Qualifier]
- cerebrospinal fluid [MeSH Qualifier]
- chemical synthesis [MeSH Qualifier]
- chemistry [MeSH Qualifier]
- classification [MeSH Qualifier]
- contraindications [MeSH Qualifier]
- deficiency [MeSH Qualifier]
- drug effects [MeSH Qualifier]
- economics [MeSH Qualifier]
- genetics [MeSH Qualifier]
- history [MeSH Qualifier]
- immunology [MeSH Qualifier]
- isolation and purification [MeSH Qualifier]
- metabolism [MeSH Qualifier]
- pharmacokinetics [MeSH Qualifier]
- pharmacology [MeSH Qualifier]
- physiology [MeSH Qualifier]
- poisoning [MeSH Qualifier]
- radiation effects [MeSH Qualifier]
- standards [MeSH Qualifier]
- supply and distribution [MeSH Qualifier]
- therapeutic use [MeSH Qualifier]
- toxicity [MeSH Qualifier]
- ultrastructure [MeSH Qualifier]
- urine [MeSH Qualifier]
Currated CISMeF NLP mapping
- Complement C5 [LOINC component]
- Complement C5 [NCIt concept]
- Complement component C5 (substance) [SNOMED CT concept]
- complement component c5, nos [SNOMED Notion]
Indexing information
- chemotactin [MeSH Supplementary Concept]
Pharmacological action(s)
- immunologic factors [MeSH Descriptor]
Record concept(s)
- complement C5 [MeSH concept]
- complement C5, precursor [MeSH concept]
Related MeSH Supplementary Concept(s)
- C5-peptide [MeSH Supplementary Concept]
- complement C5b-7 complex [MeSH Supplementary Concept]
- complement component 5 deficiency [MeSH Supplementary Concept]
- zilucoplan [MeSH Supplementary Concept]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Immunologic Factor [UMLS semantic type]
UMLS correspondences (same concept)
- Complement C5 [NCIt concept]
- Complement C5 [LOINC component]
- Complement component C5 (substance) [SNOMED CT concept]
- complement component c5, nos [SNOMED Notion]

Keyword's position in hierarchy(ies) :

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