complement C9 - CISMeF

Preferred Label : complement C9;

MeSH definition : A 63-kDa serum glycoprotein encoded by gene C9. Monomeric C9 (mC9) binds the C5b-8 complex to form C5b-9 which catalyzes the polymerization of C9 forming C5b-p9 (MEMBRANE ATTACK COMPLEX) and transmembrane channels leading to lysis of the target cell. Patients with C9 deficiency suffer from recurrent bacterial infections.;

MeSH synonym : complement component 9; complement 9; c9, complement; component 9, complement; c9 complement; complement, C9;

Wikipedia link : https://en.wikipedia.org/wiki/Complement c9;

Is substance : O;

Details

Origin ID

D003186;

UMLS CUI

C0009526;

Allowable qualifiers
- administration and dosage [MeSH Qualifier]
- adverse effects [MeSH Qualifier]
- agonists [MeSH Qualifier]
- analysis [MeSH Qualifier]
- antagonists and inhibitors [MeSH Qualifier]
- biosynthesis [MeSH Qualifier]
- cerebrospinal fluid [MeSH Qualifier]
- chemical synthesis [MeSH Qualifier]
- chemistry [MeSH Qualifier]
- classification [MeSH Qualifier]
- contraindications [MeSH Qualifier]
- deficiency [MeSH Qualifier]
- drug effects [MeSH Qualifier]
- economics [MeSH Qualifier]
- genetics [MeSH Qualifier]
- history [MeSH Qualifier]
- immunology [MeSH Qualifier]
- isolation and purification [MeSH Qualifier]
- metabolism [MeSH Qualifier]
- pharmacokinetics [MeSH Qualifier]
- pharmacology [MeSH Qualifier]
- physiology [MeSH Qualifier]
- poisoning [MeSH Qualifier]
- radiation effects [MeSH Qualifier]
- standards [MeSH Qualifier]
- supply and distribution [MeSH Qualifier]
- therapeutic use [MeSH Qualifier]
- toxicity [MeSH Qualifier]
- ultrastructure [MeSH Qualifier]
- urine [MeSH Qualifier]
Currated CISMeF NLP mapping
- Complement C9 [LOINC component]
Pharmacological action(s)
- immunologic factors [MeSH Descriptor]
Record concept(s)
- complement C9 [MeSH concept]
Related MeSH Supplementary Concept(s)
- C9 deficiency [MeSH Supplementary Concept]
- C9 deficiency with dermatomyositis [MeSH Supplementary Concept]
- complement C9 polymer [MeSH Supplementary Concept]
- complement C9b [MeSH Supplementary Concept]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Immunologic Factor [UMLS semantic type]
UMLS correspondences (same concept)
- Complement C9 [LOINC component]
- Complement component C9 (substance) [SNOMED CT concept]

Keyword's position in hierarchy(ies) :

Main resources

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