" /> Ravulizumab - CISMeF





Preferred Label : Ravulizumab;

NCIt synonyms : Ravulizumab-cwvz;

NCIt definition : A longer-acting antibody directed against terminal complement protein C5, with potential anti-inflammatory activity. Upon administration, ravulizumab binds to terminal complement protein C5, thereby blocking C5 cleavage into pro-inflammatory components and preventing the complement-mediated destruction of red blood cells (RBCs) as seen in paroxysmal nocturnal hemoglobinuria (PNH). Compared to other anti-C5 antibodies, ALXN1210 is longer-acting and allows for monthly dosing. C5, a complement pathway protein, is expressed at high levels by the liver.;

UNII : C3VX249T6L;

CAS number : 1803171-55-2;

Drug name : Ultomiris;

Molecule name : ALXN 1210; ALXN-1210;

NCI Metathesaurus CUI : CL502889;

Codes from synonyms : 94609;

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Keyword's position in hierarchy(ies) : arborescence

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09/05/2025


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