Axin-2 - CISMeF

Preferred Label : Axin-2;

NCIt synonyms : Conductin; Axil; Axis Inhibitor 2; AXIN2; Axin-2 Protein; Axis Inhibition Protein 2; Axin 2; Axin-Like Protein;

NCIt definition : Axin-2 (843 aa, 94 kDa) is encoded by the human AXIN2 gene. This protein is involved in downregulation of the Wnt signaling pathway.;

NCIt note : Axin-2 promotes beta catenin degradation.;

Details

Origin ID

C21488;

UMLS CUI

C1454580;

OMIM relation
- Axis inhibitor 2 [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Biologically Active Substance [UMLS semantic type]
UMLS correspondences (same concept)
- AXIN2 protein, human [MeSH concept]
- AXIN2 protein, human [MeSH Supplementary Concept]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_encodes_gene_product
- AXIN2 Gene [NCIt concept]
- Signaling Pathway Gene [NCIt concept]
gene_product_has_associated_anatomy
- Cytoplasm [NCIt concept]
gene_product_has_organism_source
- Human [NCIt concept]
gene_product_has_structural_domain_or_motif
- Armadillo Repeat [NCIt concept]
- DIX Domain [NCIt concept]
- GSK-Binding Domain [NCIt concept]
- RGS Domain [NCIt concept]
gene_product_plays_role_in_biological_process
- Signal Transduction [NCIt concept]

Keyword's position in hierarchy(ies) :

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