GSK-Binding Domain

Preferred Label : GSK-Binding Domain;

NCIt definition : The GSK-Binding Domain of AXIN2 mediates interaction with GSK3-Beta. Involved in regulation of the WNT signaling pathway, AXIN2 organizes an APC/Beta-Catenin/GSK3-Beta/ AXIN2 complex that leads to Beta-Catenin degradation. (NCI);

Details

Origin ID

C14104;

UMLS CUI

C1517370;

Semantic type(s)
- Amino Acid Sequence [UMLS semantic type]
is_structural_domain_or_motif_of_gene_product
- Axin-1 [NCIt concept]
- Axin-2 [NCIt concept]

Keyword's position in hierarchy(ies) :

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