Beta-Nerve Growth Factor

Preferred Label : Beta-Nerve Growth Factor;

NCIt synonyms : Nerve Growth Factor 1; NGF; Nerve Growth Factor, Beta Subunit; Beta-NGF;

NCIt related terms : nerve growth factor;

CISMeF acronym : NGFB;

NCIt definition : Beta-nerve growth factor (241 aa, 27 kDa) is encoded by the human NGF gene. This protein plays a role in both the maintenance and differentiation of sympathetic and sensory neurons.;

Alternative definition : NCI-GLOSS: A protein made by the body that causes certain nerve cells to grow and helps keep them alive.;

NCIt note : The active form of beta-nerve growth factor is produced by proteolytic cleaves that remove 121 N-terminal residues from the full length precursor protein. (UniProt);

Codes from synonyms : CDR0000449760;

Details

Origin ID

C20444;

UMLS CUI

C1571151;

Currated CISMeF NLP mapping
- nerve growth factor [MeSH Descriptor]
- nerve growth factor [MeSH concept]
- nerve growth factor [SNOMED Notion]
False automatic mappings
- Nerve growth factor (substance) [SNOMED CT concept]
- nerve growth factor (10-25,75-88) [MeSH concept]
- nerve growth factor (10-25,75-88) [MeSH Supplementary Concept]
- nerve growth factor (75-88) [MeSH concept]
- nerve growth factor (75-88) [MeSH Supplementary Concept]
- nerve growth factors [MeSH Descriptor]
- nerve growth factors [MeSH concept]
OMIM relation
- Nerve growth factor [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Biologically Active Substance [UMLS semantic type]
UMLS correspondences (same concept)
- NGF protein, human [MeSH concept]
- NGF protein, human [MeSH Supplementary Concept]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_encodes_gene_product
- Growth Factor Gene [NCIt concept]
- NGF Gene [NCIt concept]
gene_product_has_associated_anatomy
- Extracellular Space [NCIt concept]
gene_product_is_element_in_pathway
- Apoptosis Pathway [NCIt concept]
- Erk1/Erk2 MAPK Signaling Pathway [NCIt concept]
- MAP Kinase Downregulation Pathway [NCIt concept]
- MAPK Signaling Pathway [NCIt concept]
- NTRK1/PI3K/PLC-Gamma Signaling Pathway [NCIt concept]
- Nerve Growth Factor Pathway [NCIt concept]
- Nerve Growth Factor Receptor Signaling Pathway [NCIt concept]
- Neurotrophic Factor-Mediated NTRK1 Signaling Pathway [NCIt concept]
- Neurotrophin Signaling Pathway [NCIt concept]
- Trka Receptor Signaling Pathway [NCIt concept]
gene_product_plays_role_in_biological_process
- Cell Proliferation Regulatory Process [NCIt concept]
- Neural Development [NCIt concept]
- Receptor Signaling [NCIt concept]
- Signal Transduction [NCIt concept]
is_target
- Fulranumab [NCIt concept]
- Tanezumab [NCIt concept]

Keyword's position in hierarchy(ies) :

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