Trophoblast Glycoprotein

Preferred Label : Trophoblast Glycoprotein;

NCIt synonyms : Wnt-Activated Inhibitory Factor 1; 5T4 Oncofetal Antigen; TPBG; 5T4 Oncotrophoblast Glycoprotein; 5T4 Oncofetal Trophoblast Glycoprotein; M6P1; WAIF1;

NCIt definition : Trophoblast glycoprotein (420 aa, 46 kDa) is encoded by the human TPBG gene. This protein is involved in cell adhesion and Wnt-signaling.;

Details

Origin ID

C186697;

UMLS CUI

C1437272;

OMIM relation
- Trophoblast glycoprotein [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Immunologic Factor [UMLS semantic type]
UMLS correspondences (same concept)
- trophoblastic glycoprotein 5T4, human [MeSH Supplementary Concept]
- trophoblastic glycoprotein 5T4, human [MeSH concept]
gene_encodes_gene_product
- Signaling Pathway Gene [NCIt concept]
- TPBG Gene [NCIt concept]
gene_product_expressed_in_tissue
- Trophoblast [NCIt concept]
gene_product_has_associated_anatomy
- Plasma Membrane [NCIt concept]
- Trophoblastic Cell [NCIt concept]
gene_product_has_chemical_classification
- Transmembrane Protein [NCIt concept]
gene_product_has_structural_domain_or_motif
- Cysteine-Rich Domain [NCIt concept]
- Leucine-Rich Repeat [NCIt concept]
- Transmembrane Domain [NCIt concept]
gene_product_plays_role_in_biological_process
- Chemotactic Process [NCIt concept]
- Signal Transduction [NCIt concept]
is_target
- Anti-4-1BB/5T4 Bispecific Antibody ALG.APV-527 [NCIt concept]
- Anti-5T4 Antibody-Drug Conjugate PF-06263507 [NCIt concept]
- Anti-5T4 Antibody-drug Conjugate ASN004 [NCIt concept]
- Anti-5T4 Antibody-drug Conjugate SYD1875 [NCIt concept]
- Anti-CD3/Anti-5T4 Bispecific Antibody GEN1044 [NCIt concept]
- ChAdOx1-PSA/PAP/STEAP1/5T4 Prostate Cancer Vaccine ChAdOx1-PCAQ [NCIt concept]
- MVA-PSA/PAP/STEAP1/5T4 Prostate Cancer Vaccine MVA-PCAQ [NCIt concept]
- Recombinant Modified Vaccinia Ankara-5T4 Vaccine [NCIt concept]

Keyword's position in hierarchy(ies) :

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