Preferred Label : Recombinant Modified Vaccinia Ankara-5T4 Vaccine;
NCIt synonyms : Recombinant MVA-5T4 Vaccine; Recombinant Pox Virus Encoding 5T4 Vaccine;
NCIt related terms : OXB-301;
NCIt definition : A cancer vaccine comprised of a recombinant modified vaccinia Ankara (MVA) viral vector
encoding the 5T4 fetal oncoprotein (MVA-h5T4). Vaccination with recombinant modified
vaccinia Ankara-5T4 vaccine may stimulate the host immune system to mount a humoral
and cytotoxic T lymphocyte (CTL) response against tumor cells expressing 5T4 fetal
oncoprotein antigen, resulting in tumor cell lysis. The MVA viral vector, derived
from the replication-competent strain Ankara, is a highly attenuated, replication-defective
vaccinia strain incapable of virion assembly.;
UNII : P258UUW1OD;
Drug name : TroVax;
Origin ID : C49087;
UMLS CUI : C1709858;
Semantic type(s)
- concept_is_in_subset
- has_target
