ChAdOx1-PSA/PAP/STEAP1/5T4 Prostate Cancer Vaccine ChAdOx1-PCAQ

Preferred Label : ChAdOx1-PSA/PAP/STEAP1/5T4 Prostate Cancer Vaccine ChAdOx1-PCAQ;

NCIt synonyms : ChAdOx1-PCAQ; Recombinant ChAdOx1 PSA/PAP/STEAP1/5T4 Vaccine ChAdOx1-PCAQ;

NCIt definition : A cancer vaccine consisting of recombinant non-replicating chimpanzee adenovirus Oxford 1 (ChAdOx1) viral vector encoding genes for the prostate cancer-associated antigens prostate-specific antigen (PSA), prostatic acid phosphatase (PAP), six-transmembrane epithelial antigen of the prostate 1 (STEAP1), and 5T4 oncofetal antigen, with potential immunostimulatory and antineoplastic activities. Upon administration, ChAdOx1-PSA/PAP/STEAP1/5T4 prostate cancer vaccine ChAdOx1-PCAQ expresses PSA, PAP, STEAP1 and 5T4 peptides, which may elicit humoral and cellular immune responses against prostate cancer cells expressing these antigens.;

NCI Metathesaurus CUI : CL1906842;

Details

Origin ID

C199487;

UMLS CUI

C5855621;

Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Immunologic Factor [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
concept_is_in_subset
- CTRP Agent Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
- GDC Terminology [NCIt concept]
- GDC Therapeutic Agent Terminology [NCIt concept]
- NCI Drug Dictionary Terminology [NCIt concept]
- NCIt Antineoplastic Agent Terminology [NCIt concept]
has_target
- Metalloreductase STEAP1 [NCIt concept]
- Prostate-Specific Antigen [NCIt concept]
- Prostatic Acid Phosphatase [NCIt concept]
- Trophoblast Glycoprotein [NCIt concept]

Keyword's position in hierarchy(ies) :

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