PRKCD wt Allele

Preferred Label : PRKCD wt Allele;

NCIt synonyms : MAY1; Protein Kinase C, Delta Gene; SDK1; Protein Kinase C Delta wt Allele; PKCD; ALPS3; nPKC-delta; Sphingosine-Dependent Protein Kinase-1 Gene; CVID9;

NCIt definition : Human PRKCD wild-type allele is located in the vicinity of 3p21.1 and is approximately 37 kb in length. This allele, which encodes protein kinase C delta type protein, is involved in both cell death and cell survival. Mutation of the gene is associated with autoimmune lymphoproliferative syndrome 3.;

NCI Metathesaurus CUI : CL551928;

GenBank Accession Number : NM_001316327;

Details

Origin ID

C150119;

UMLS CUI

C4723673;

Automatic exact mappings (from CISMeF team)
- Autoimmune lymphoproliferative syndrome, type III [OMIM Phenotype]
- Protein kinase C, delta [OMIM gene]
- Sidekick cell adhesion molecule 1 [OMIM gene]
- autoimmune lymphoproliferative syndrome type 3 [DO Concept]
- calcium-independent protein kinase C [MeSH Supplementary Concept]
- nPKC-delta [MeSH concept]
- protein kinase C activity [GO term]
OMIM relation
- Protein kinase C, delta [OMIM gene]
Semantic type(s)
- Gene or Genome [UMLS semantic type]
gene_found_in_organism
- Human [NCIt concept]
gene_in_chromosomal_location
- 3p21.1 [NCIt concept]
gene_is_element_in_pathway
- Alpha-Synuclein Signaling Pathway [NCIt concept]
- Autophagy Regulation Pathway [NCIt concept]
- Calcineurin-Dependent NFAT Signaling Pathway in Lymphocytes [NCIt concept]
- Ceramide Signaling Pathway PID [NCIt concept]
- Chemokine Signaling Pathway [NCIt concept]
- Epidermal Growth Factor Receptor Downstream Signaling Pathway [NCIt concept]
- Fc Gamma Receptor-Mediated Phagocytosis Pathway [NCIt concept]
- Gonadotropin-Releasing Hormone Signaling Pathway [NCIt concept]
- HIV-I Nef in Apoptosis Pathway [NCIt concept]
- Hedgehog Signaling Events Mediated by Gli Family Proteins [NCIt concept]
- IGF1 Pathway [NCIt concept]
- IL6-Mediated Signaling Pathway [NCIt concept]
- Interferon-Gamma Signaling Pathway [NCIt concept]
- Keratinocyte Differentiation Pathway [NCIt concept]
- Lysophosphatidic Acid Receptor Signaling Pathway [NCIt concept]
- NOD-Like Receptor Signaling Pathway [NCIt concept]
- NTRK1/MAPK Signaling Pathway [NCIt concept]
- NTRK1/PI3K/PLC-Gamma Signaling Pathway [NCIt concept]
- Neurotrophin Signaling Pathway [NCIt concept]
- PDGFR-beta Signaling Pathway [NCIt concept]
- Syndecan-2-Mediated Signaling Pathway [NCIt concept]
- Syndecan-4-Mediated Signaling Pathway [NCIt concept]
- Thromboxane A2 Receptor Family Signaling Pathway [NCIt concept]
- Type II Diabetes Mellitus Pathway [NCIt concept]
- VEGFR1 and VEGFR2 Signaling [NCIt concept]
- Vascular Smooth Muscle Contraction Pathway [NCIt concept]
- p53 Pathway for Transcriptional Regulation [NCIt concept]
gene_plays_role_in_process
- Chemotactic Process [NCIt concept]
- Cytoskeletal Modeling [NCIt concept]
- Phosphorylation Process [NCIt concept]
- Regulation of Cell Death Process [NCIt concept]
- Serine/Threonine Phosphorylation [NCIt concept]
- Signal Transduction [NCIt concept]

Keyword's position in hierarchy(ies) :

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