Denticleless Protein Homolog

Preferred Label : Denticleless Protein Homolog;

NCIt synonyms : DDB1- and CUL4-Associated Factor 2; Lethal(2) Denticleless Protein Homolog; Retinoic Acid-Regulated Nuclear Matrix-Associated Protein;

NCIt definition : Denticleless protein homolog (730 aa, 79 kDa) is encoded by the human DTL gene. This protein plays a role in the regulation of E3 ubiquitin ligase activity.;

Details

Origin ID

C101610;

UMLS CUI

C3540508;

OMIM relation
- Denticleless e3 ubiquitin protein ligase homolog [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
gene_encodes_gene_product
- DTL Gene [NCIt concept]
- Regulatory Gene [NCIt concept]
gene_product_has_associated_anatomy
- Centrosome [NCIt concept]
gene_product_has_structural_domain_or_motif
- WD Repeat [NCIt concept]
gene_product_is_element_in_pathway
- B-Cell Immune Response Pathway [NCIt concept]
gene_product_is_physical_part_of
- Ubiquitin Protein Ligase [NCIt concept]
gene_product_plays_role_in_biological_process
- Monoubiquitination [NCIt concept]
- Polyubiquitination [NCIt concept]
- Ubiquitinated Protein Degradation [NCIt concept]
- Ubiquitination [NCIt concept]

Keyword's position in hierarchy(ies) :

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