polycomb repressive complex 2

Preferred Label : polycomb repressive complex 2;

MeSH definition : A multisubunit polycomb protein complex that catalyzes the METHYLATION of chromosomal HISTONE H3. It works in conjunction with POLYCOMB REPRESSIVE COMPLEX 1 to effect EPIGENETIC REPRESSION.;

Registry Number MeSH : EC 2.1.1.43;

Is substance : O;

UNII : EC 2.1.1.43;

Details

Origin ID

D063151;

UMLS CUI

C3494414;

Allowable qualifiers
- administration and dosage [MeSH Qualifier]
- adverse effects [MeSH Qualifier]
- agonists [MeSH Qualifier]
- analysis [MeSH Qualifier]
- antagonists and inhibitors [MeSH Qualifier]
- biosynthesis [MeSH Qualifier]
- blood [MeSH Qualifier]
- cerebrospinal fluid [MeSH Qualifier]
- chemical synthesis [MeSH Qualifier]
- chemistry [MeSH Qualifier]
- classification [MeSH Qualifier]
- contraindications [MeSH Qualifier]
- deficiency [MeSH Qualifier]
- drug effects [MeSH Qualifier]
- economics [MeSH Qualifier]
- genetics [MeSH Qualifier]
- history [MeSH Qualifier]
- immunology [MeSH Qualifier]
- isolation and purification [MeSH Qualifier]
- metabolism [MeSH Qualifier]
- pharmacokinetics [MeSH Qualifier]
- pharmacology [MeSH Qualifier]
- physiology [MeSH Qualifier]
- poisoning [MeSH Qualifier]
- radiation effects [MeSH Qualifier]
- standards [MeSH Qualifier]
- supply and distribution [MeSH Qualifier]
- therapeutic use [MeSH Qualifier]
- toxicity [MeSH Qualifier]
- ultrastructure [MeSH Qualifier]
- urine [MeSH Qualifier]
Automatic exact mappings (from CISMeF team)
- Histone-Lysine N-Methyltransferase 2C [NCIt concept]
- Histone-Lysine N-Methyltransferase 2E [NCIt concept]
- Histone-Lysine N-Methyltransferase EZH2 [NCIt concept]
- Histone-Lysine N-Methyltransferase H3 Lysine-79 Specific [NCIt concept]
- Histone-Lysine N-Methyltransferase KMT5B [NCIt concept]
- Histone-Lysine N-Methyltransferase KMT5C [NCIt concept]
- Histone-Lysine N-Methyltransferase SETD2 [NCIt concept]
- Histone-Lysine N-Methyltransferase SETD7 [NCIt concept]
- Histone-Lysine N-Methyltransferase SETDB1 [NCIt concept]
- Histone-Lysine N-Methyltransferase SUV39H1 [NCIt concept]
- Histone-Lysine N-Methyltransferase SUV39H2 [NCIt concept]
- N-Lysine Methyltransferase KMT5A [NCIt concept]
- Polycomb Repressive Complex 2 [NCIt concept]
Record concept(s)
- polycomb repressive complex 2 [MeSH concept]
Related MeSH Supplementary Concept(s)
- E(z) protein, drosophila [MeSH Supplementary Concept]
- EED protein, drosophila [MeSH Supplementary Concept]
- EED protein, human [MeSH Supplementary Concept]
- EZH1 protein, human [MeSH Supplementary Concept]
- EZH1 protein, rat [MeSH Supplementary Concept]
- EZH2 protein, human [MeSH Supplementary Concept]
- EZH2 protein, rat [MeSH Supplementary Concept]
- EZH2 protein, xenopus [MeSH Supplementary Concept]
- Ezh1 protein, mouse [MeSH Supplementary Concept]
- Ezh2 protein, mouse [MeSH Supplementary Concept]
- JARID2 protein, human [MeSH Supplementary Concept]
- Jarid2 protein, mouse [MeSH Supplementary Concept]
- MTF2 protein, human [MeSH Supplementary Concept]
- Mtf2 protein, mouse [MeSH Supplementary Concept]
- PHC2 protein, human [MeSH Supplementary Concept]
- PRC2 protein, arabidopsis [MeSH Supplementary Concept]
- Phc2 protein, mouse [MeSH Supplementary Concept]
- Su(z)12 protein, drosophila [MeSH Supplementary Concept]
- Suz12 protein, mouse [MeSH Supplementary Concept]
- Suz12 protein, xenopus [MeSH Supplementary Concept]
- eed protein, mouse [MeSH Supplementary Concept]
- esc protein, drosophila [MeSH Supplementary Concept]
- ezh1 protein, zebrafish [MeSH Supplementary Concept]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Enzyme [UMLS semantic type]
UMLS correspondences (same concept)
- Polycomb Repressive Complex 2 [NCIt concept]

Keyword's position in hierarchy(ies) :

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