Receptor-Interacting protein Serine-Threonine kinases

Preferred Label : Receptor-Interacting protein Serine-Threonine kinases;

MeSH definition : A family of serine-threonine kinases that plays a role in intracellular signal transduction by interacting with a variety of signaling adaptor proteins such as CRADD SIGNALING ADAPTOR PROTEIN; TNF RECEPTOR-ASSOCIATED FACTOR 2; and TNF RECEPTOR-ASSOCIATED DEATH DOMAIN PROTEIN. Although they were initially described as death domain-binding adaptor proteins, members of this family may contain other protein-binding domains such as those involving caspase activation and recruitment.;

MeSH synonym : rip serine threonine kinases; rip serine-threonine kinases; kinases, rip serine-threonine; serine-threonine kinases, rip; receptor interacting protein serine threonine kinases;

CISMeF synonym : EC 2.7.1.37; EC 2.7.1.-;

MeSH hyponym : Receptor-Interacting protein Serine-Threonine kinase 1; Receptor-Interacting protein Serine-Threonine kinase 3; Receptor Interacting Protein Serine Threonine Kinase 3; Receptor Interacting Protein Serine Threonine Kinase 1; Receptor Interacting Protein RIP; RIP Serine-Threonine Kinase; Kinase, RIP Serine-Threonine; RIP Serine Threonine Kinase; Serine-Threonine Kinase, RIP; RIP (Receptor Interacting Protein);

MeSH Related Number : Receptor-Interacting protein Serine-Threonine kinase 3; Receptor-Interacting protein Serine-Threonine kinase 1; EC 2.7.11.1;

Registry Number MeSH : EC 2.7.11.1;

Related CAS MeSH : EC 2.7.11.1 (Receptor-Interacting protein Serine-Threonine kinase 3); EC 2.7.11.1 (Receptor-Interacting protein Serine-Threonine kinase 1);

Is substance : O;

UNII : EC 2.7.11.1;

Details

Origin ID

D053422;

UMLS CUI

C1720974;

Allowable qualifiers
- administration and dosage [MeSH Qualifier]
- adverse effects [MeSH Qualifier]
- analysis [MeSH Qualifier]
- antagonists and inhibitors [MeSH Qualifier]
- biosynthesis [MeSH Qualifier]
- blood [MeSH Qualifier]
- cerebrospinal fluid [MeSH Qualifier]
- chemical synthesis [MeSH Qualifier]
- chemistry [MeSH Qualifier]
- classification [MeSH Qualifier]
- contraindications [MeSH Qualifier]
- deficiency [MeSH Qualifier]
- drug effects [MeSH Qualifier]
- economics [MeSH Qualifier]
- genetics [MeSH Qualifier]
- history [MeSH Qualifier]
- immunology [MeSH Qualifier]
- isolation and purification [MeSH Qualifier]
- metabolism [MeSH Qualifier]
- pharmacokinetics [MeSH Qualifier]
- pharmacology [MeSH Qualifier]
- physiology [MeSH Qualifier]
- poisoning [MeSH Qualifier]
- radiation effects [MeSH Qualifier]
- standards [MeSH Qualifier]
- supply and distribution [MeSH Qualifier]
- therapeutic use [MeSH Qualifier]
- toxicity [MeSH Qualifier]
- ultrastructure [MeSH Qualifier]
- urine [MeSH Qualifier]
Automatic exact mappings (from CISMeF team)
- 5'-AMP-Activated Protein Kinase Catalytic Subunit Alpha-2 [NCIt concept]
- Aurora Kinase C [NCIt concept]
- Cell Division Cycle 7-Related Protein Kinase [NCIt concept]
- Cyclin-Dependent Kinase 10 [NCIt concept]
- Cyclin-Dependent Kinase 2 [NCIt concept]
- Cyclin-Dependent Kinase 3 [NCIt concept]
- Leucine-Rich Repeat Serine/Threonine-Protein Kinase 2 [NCIt concept]
- MAP Kinase-Interacting Serine/Threonine-Protein Kinase 1 [NCIt concept]
- MAP Kinase-Interacting Serine/Threonine-Protein Kinase 2 [NCIt concept]
- Mitotic Checkpoint Serine/Threonine-Protein Kinase BUB1 Beta [NCIt concept]
- Nik-Related Protein Kinase [NCIt concept]
- Receptor-Interacting Serine/Threonine-Protein Kinase 3 [NCIt concept]
- Serine/Threonine-Protein Kinase 33 [NCIt concept]
- Serine/Threonine-Protein Kinase Nek10 [NCIt concept]
- Transcription Initiation Factor TFIID Subunit 1 [NCIt concept]
Record concept(s)
- Receptor-Interacting protein Serine-Threonine kinase 1 [MeSH concept]
- Receptor-Interacting protein Serine-Threonine kinase 3 [MeSH concept]
- Receptor-Interacting protein Serine-Threonine kinases [MeSH concept]
Related MeSH Supplementary Concept(s)
- DSTYK protein, human [MeSH Supplementary Concept]
- DSTYK protein, mouse [MeSH Supplementary Concept]
- RIPK1 protein, human [MeSH Supplementary Concept]
- RIPK1 protein, rat [MeSH Supplementary Concept]
- RIPK2 protein, zebrafish [MeSH Supplementary Concept]
- RIPK3 protein, human [MeSH Supplementary Concept]
- Ripk1 protein, mouse [MeSH Supplementary Concept]
- Ripk2 protein, mouse [MeSH Supplementary Concept]
- Ripk3 protein, mouse [MeSH Supplementary Concept]
- Ripk3 protein, rat [MeSH Supplementary Concept]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Enzyme [UMLS semantic type]

Keyword's position in hierarchy(ies) :

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