DNA-Activated protein kinase

Preferred Label : DNA-Activated protein kinase;

MeSH definition : A serine-threonine protein kinase that, when activated by DNA, phosphorylates several DNA-binding protein substrates including the TUMOR SUPPRESSOR PROTEIN P53 and a variety of TRANSCRIPTION FACTORS.;

MeSH synonym : dna-dependent protein serine-threonine kinase; kinase, dna-dependent protein; protein kinase, dna-activated; kinase, dna-activated protein; dna-dependent protein kinase; dna dependent protein kinase; protein kinase, dna-dependent; dna dependent protein serine threonine kinase; DNA activated protein kinase;

CISMeF synonym : EC 2.7.1.37;

Registry Number MeSH : EC 2.7.11.1;

Is substance : O;

UNII : EC 2.7.11.1;

Details

Origin ID

D051747;

UMLS CUI

C0212694;

Allowable qualifiers
- administration and dosage [MeSH Qualifier]
- adverse effects [MeSH Qualifier]
- analysis [MeSH Qualifier]
- antagonists and inhibitors [MeSH Qualifier]
- biosynthesis [MeSH Qualifier]
- blood [MeSH Qualifier]
- cerebrospinal fluid [MeSH Qualifier]
- chemical synthesis [MeSH Qualifier]
- chemistry [MeSH Qualifier]
- classification [MeSH Qualifier]
- contraindications [MeSH Qualifier]
- deficiency [MeSH Qualifier]
- drug effects [MeSH Qualifier]
- economics [MeSH Qualifier]
- genetics [MeSH Qualifier]
- history [MeSH Qualifier]
- immunology [MeSH Qualifier]
- isolation and purification [MeSH Qualifier]
- metabolism [MeSH Qualifier]
- pharmacokinetics [MeSH Qualifier]
- pharmacology [MeSH Qualifier]
- physiology [MeSH Qualifier]
- poisoning [MeSH Qualifier]
- radiation effects [MeSH Qualifier]
- standards [MeSH Qualifier]
- supply and distribution [MeSH Qualifier]
- therapeutic use [MeSH Qualifier]
- toxicity [MeSH Qualifier]
- ultrastructure [MeSH Qualifier]
- urine [MeSH Qualifier]
Automatic exact mappings (from CISMeF team)
- 5'-AMP-Activated Protein Kinase Catalytic Subunit Alpha-2 [NCIt concept]
- Aurora Kinase C [NCIt concept]
- Cell Division Cycle 7-Related Protein Kinase [NCIt concept]
- Cyclin-Dependent Kinase 10 [NCIt concept]
- Cyclin-Dependent Kinase 2 [NCIt concept]
- Cyclin-Dependent Kinase 3 [NCIt concept]
- DNA-Dependent Protein Kinase Catalytic Subunit [NCIt concept]
- Leucine-Rich Repeat Serine/Threonine-Protein Kinase 2 [NCIt concept]
- MAP Kinase-Interacting Serine/Threonine-Protein Kinase 1 [NCIt concept]
- MAP Kinase-Interacting Serine/Threonine-Protein Kinase 2 [NCIt concept]
- Mitotic Checkpoint Serine/Threonine-Protein Kinase BUB1 Beta [NCIt concept]
- Nik-Related Protein Kinase [NCIt concept]
- PRKDC wt Allele [NCIt concept]
- Protein kinase, dna-activated, catalytic subunit [OMIM gene]
- Serine/Threonine-Protein Kinase 33 [NCIt concept]
- Serine/Threonine-Protein Kinase Nek10 [NCIt concept]
- Transcription Initiation Factor TFIID Subunit 1 [NCIt concept]
- protein kinase, DNA-activated, catalytic subunit [ORDO Gene]
Indexing information
- 2-(4-ethylpiperazin-1-yl)-N-(4-(2-morpholino-4-oxo-4H-chromen-8-yl)dibenzo(b,d)thiophen-1-yl)acetamide [MeSH Supplementary Concept]
- 2-(4-methoxyphenyl)-6-(morpholin-4-yl)pyran-4-one [MeSH Supplementary Concept]
- 2-N-morpholino-8-dibenzofuranylchromen-4-one [MeSH Supplementary Concept]
- 4,5-dimethoxy-2-nitrobenzaldehyde [MeSH Supplementary Concept]
- 8-dibenzothiophen-4-yl-2-morpholin-4-yl-chromen-4-one [MeSH Supplementary Concept]
Record concept(s)
- DNA-Activated protein kinase [MeSH concept]
Related MeSH Supplementary Concept(s)
- PRKDC protein, human [MeSH Supplementary Concept]
- Prkdc protein, rat [MeSH Supplementary Concept]
- Prkdc protein, zebrafish [MeSH Supplementary Concept]
- prkdc protein, mouse [MeSH Supplementary Concept]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Enzyme [UMLS semantic type]

Keyword's position in hierarchy(ies) :

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