proto-oncogene proteins c-raf

Preferred Label : proto-oncogene proteins c-raf;

MeSH definition : A ubiquitously expressed raf kinase subclass that plays an important role in SIGNAL TRANSDUCTION. The c-raf Kinases are MAP kinase kinase kinases that have specificity for MAP KINASE KINASE 1 and MAP KINASE KINASE 2.;

MeSH synonym : c-raf kinases; kinase, craf1; kinase p74(raf-1); proteins, c-raf; proto oncogene protein c raf; raf-1, kinase; raf-1 kinase; proteins c-raf, proto-oncogene; c-raf, proto-oncogene proteins; c-raf proteins; c raf proteins; craf1 kinase; kinase raf-1; kinase raf 1; proto-oncogene protein c-raf; protein c-raf, proto-oncogene; c-raf, proto-oncogene protein; kinase, raf-1; raf 1 kinase; kinases, c-raf; c raf kinases; proto oncogene proteins c raf;

CISMeF synonym : EC 2.7.1.37;

Registry Number MeSH : EC 2.7.11.1;

Is substance : O;

UNII : EC 2.7.11.1;

Details

Origin ID

D019908;

UMLS CUI

C0139030;

Allowable qualifiers
- administration and dosage [MeSH Qualifier]
- adverse effects [MeSH Qualifier]
- analysis [MeSH Qualifier]
- antagonists and inhibitors [MeSH Qualifier]
- biosynthesis [MeSH Qualifier]
- blood [MeSH Qualifier]
- cerebrospinal fluid [MeSH Qualifier]
- chemical synthesis [MeSH Qualifier]
- chemistry [MeSH Qualifier]
- classification [MeSH Qualifier]
- contraindications [MeSH Qualifier]
- deficiency [MeSH Qualifier]
- drug effects [MeSH Qualifier]
- economics [MeSH Qualifier]
- genetics [MeSH Qualifier]
- history [MeSH Qualifier]
- immunology [MeSH Qualifier]
- isolation and purification [MeSH Qualifier]
- metabolism [MeSH Qualifier]
- pharmacokinetics [MeSH Qualifier]
- pharmacology [MeSH Qualifier]
- physiology [MeSH Qualifier]
- poisoning [MeSH Qualifier]
- radiation effects [MeSH Qualifier]
- standards [MeSH Qualifier]
- supply and distribution [MeSH Qualifier]
- therapeutic use [MeSH Qualifier]
- toxicity [MeSH Qualifier]
- ultrastructure [MeSH Qualifier]
- urine [MeSH Qualifier]
Automatic exact mappings (from CISMeF team)
- 5'-AMP-Activated Protein Kinase Catalytic Subunit Alpha-2 [NCIt concept]
- Aurora Kinase C [NCIt concept]
- B-Raf proto-oncogene, serine/threonine kinase [ORDO Gene]
- Cell Division Cycle 7-Related Protein Kinase [NCIt concept]
- Cyclin-Dependent Kinase 10 [NCIt concept]
- Cyclin-Dependent Kinase 2 [NCIt concept]
- Cyclin-Dependent Kinase 3 [NCIt concept]
- Leucine-Rich Repeat Serine/Threonine-Protein Kinase 2 [NCIt concept]
- MAP Kinase-Interacting Serine/Threonine-Protein Kinase 1 [NCIt concept]
- MAP Kinase-Interacting Serine/Threonine-Protein Kinase 2 [NCIt concept]
- Mitotic Checkpoint Serine/Threonine-Protein Kinase BUB1 Beta [NCIt concept]
- Nik-Related Protein Kinase [NCIt concept]
- RAF Proto-Oncogene Serine/Threonine-Protein Kinase [NCIt concept]
- Serine/Threonine-Protein Kinase 33 [NCIt concept]
- Serine/Threonine-Protein Kinase Nek10 [NCIt concept]
- Transcription Initiation Factor TFIID Subunit 1 [NCIt concept]
Indexing information
- 1-(4-(1H-pyrazolo(3,4-d)pyrimidin-4-yloxy)phenyl)-3-(4-chloro-3-(trifluoromethyl)phenyl)urea [MeSH Supplementary Concept]
- 5-iodo-3-((3,5-dibromo-4-hydroxyphenyl)methylene)-2-indolinone [MeSH Supplementary Concept]
- ISIS 5132 [MeSH Supplementary Concept]
- lin-45 protein, C elegans [MeSH Supplementary Concept]
- ras-dependent mitogen-activated protein kinase kinase kinase [MeSH Supplementary Concept]
Record concept(s)
- Proto-Oncogene proteins c-raf [MeSH concept]
Related MeSH Supplementary Concept(s)
- Phf21a protein, mouse [MeSH Supplementary Concept]
- Raf protein, Drosophila [MeSH Supplementary Concept]
- Raf1 protein, human [MeSH Supplementary Concept]
- Raf1 protein, mouse [MeSH Supplementary Concept]
- Raf1 protein, rat [MeSH Supplementary Concept]
- c-mil protein, gallus gallus [MeSH Supplementary Concept]
- proto-oncogene protein v-RAF1, pig [MeSH Supplementary Concept]
See also
- oncogene proteins v-raf [MeSH Descriptor]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Enzyme [UMLS semantic type]

Keyword's position in hierarchy(ies) :

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