neuroprotective agents

Preferred Label : neuroprotective agents;

MeSH definition : Drugs intended to prevent damage to the brain or spinal cord from ischemia, stroke, convulsions, or trauma. Some must be administered before the event, but others may be effective for some time after. They act by a variety of mechanisms, but often directly or indirectly minimize the damage produced by endogenous excitatory amino acids.;

MeSH synonym : neuroprotectants; agents, neuroprotective; neuroprotective drugs; drugs, neuroprotective; Neuroprotectant; Neuroprotective Agent; Agent, Neuroprotective; Neuroprotective Drug; Drug, Neuroprotective;

Related MeSH term : neuroprotective effect; Effect, Neuroprotective; Neuroprotective Effects; Effects, Neuroprotective;

MeSH annotation : note entry term NEUROPROTECTIVE EFFECT: use only for the neuroprotective effect of a chemical substance;

Is substance : O;

action pharmacologique : O;

Details

Origin ID

D018696;

UMLS CUI

C0242912;

ATC code(s)
- riluzole [ATC Code]
ATC code(s)
- tirilazad [ATC Code]
Allowable qualifiers
- administration and dosage [MeSH Qualifier]
- adverse effects [MeSH Qualifier]
- agonists [MeSH Qualifier]
- analysis [MeSH Qualifier]
- antagonists and inhibitors [MeSH Qualifier]
- blood [MeSH Qualifier]
- cerebrospinal fluid [MeSH Qualifier]
- chemical synthesis [MeSH Qualifier]
- chemistry [MeSH Qualifier]
- classification [MeSH Qualifier]
- contraindications [MeSH Qualifier]
- economics [MeSH Qualifier]
- history [MeSH Qualifier]
- immunology [MeSH Qualifier]
- isolation and purification [MeSH Qualifier]
- metabolism [MeSH Qualifier]
- pharmacokinetics [MeSH Qualifier]
- pharmacology [MeSH Qualifier]
- poisoning [MeSH Qualifier]
- radiation effects [MeSH Qualifier]
- standards [MeSH Qualifier]
- supply and distribution [MeSH Qualifier]
- therapeutic use [MeSH Qualifier]
- toxicity [MeSH Qualifier]
- urine [MeSH Qualifier]
Automatic exact mappings (from CISMeF team)
- Neuroprotection [NCIt concept]
- Neuroprotection [MedDRA LLT]
- Neuroprotective agent [PASCAL theme]
- obsolete neuroprotection [GO term]
Currated CISMeF NLP mapping
- Neuroprotective Agent [NCIt concept]
False automatic mappings
- neuroprotection [Disease (Nov.)]
Indexing information
- (M)-bicelaphanol A [MeSH Supplementary Concept]
- 1'-hydroxymethyl-phenyl 4-hydroxy-3-(4'-hydroxybenzyl) benzyl ether [MeSH Supplementary Concept]
- 2,2'-dithienyl diselenide [MeSH Supplementary Concept]
- 2-((2,6-dichlorobenzylidene)amino)-5,6-dihydro-4H-cyclopenta(b)thiophene-3-carbonitrile [MeSH Supplementary Concept]
- 2-(4-methoxyphenyl)ethyl-2-acetamido-2-deoxyglucopyranoside [MeSH Supplementary Concept]
- 2alpha-methoxy-6-O-methyllycorenine [MeSH Supplementary Concept]
- 3-(fur-2-yl)-10-(2-phenylethyl)-(1,2,4)triazino(4,3-a)benzimidazol-4(10H)-one [MeSH Supplementary Concept]
- 3-O-demethylswertipunicoside [MeSH Supplementary Concept]
- 4,7-dihydroxy-5-methyl-2-(2-oxopropyl)indan-1,3-dione [MeSH Supplementary Concept]
- 4-((4-(((4-amino-2,3,5,6-tetramethylanilino)acetyl)(methyl)amino)-1-piperidinyl)methyl)benzamide [MeSH Supplementary Concept]
- 4-(3,4-dimethoxyphenyl)-3-(naphthalen-2-yl)-2(5H)-furanone [MeSH Supplementary Concept]
- 4-(3-(2-(2-(4-acetoxy-3,5-dimethoxybenzoyloxy)ethoxy)ethylamino)-3-oxoprop-1-enyl)-1,2-phenylene diacetate [MeSH Supplementary Concept]
- 4-(4'-hydroxybenzyl)phenyl glucoside [MeSH Supplementary Concept]
- 4-acetyl-3-methyl-6-(2-bromophenyl)pyrano(3,4-c)pyran-1,8-dione [MeSH Supplementary Concept]
- 4R,6R-cembratrienediol [MeSH Supplementary Concept]
- 5-((3,4-methylenedioxyphenylethane)methylamino)-1-p-hydroxyphenyl-1-penten-3-one [MeSH Supplementary Concept]
- 7-(4-(diethylamino)butoxy)-5-hydroxy-3-(4-hydroxyphenyl)-4H-chromen-4-one [MeSH Supplementary Concept]
- AC-186 [MeSH Supplementary Concept]
- B355252 [MeSH Supplementary Concept]
- BL-1023 [MeSH Supplementary Concept]
- CD-101 [MeSH Supplementary Concept]
- CFM6104 [MeSH Supplementary Concept]
- CPC 211 [MeSH Supplementary Concept]
- CopA3 peptide, copris tripartitus [MeSH Supplementary Concept]
- D-JNKI-1 [MeSH Supplementary Concept]
- Desflurane [MeSH Descriptor]
- EUK-172 [MeSH Supplementary Concept]
- Felbamate [MeSH Descriptor]
- JO 1994 [MeSH Supplementary Concept]
- JO 1997 [MeSH Supplementary Concept]
- K456 compound [MeSH Supplementary Concept]
- K458 compound [MeSH Supplementary Concept]
- KMS80013 [MeSH Supplementary Concept]
- KU-32 compound [MeSH Supplementary Concept]
- LDN-OSU-0212320 [MeSH Supplementary Concept]
- Latanoprost [MeSH Descriptor]
- N(1)-(quinolin-2-ylmethyl)butane-1,4-diamine [MeSH Supplementary Concept]
- N-(3-chloro-1,4-dihydro-1,4-dioxo-2-naphthalenyl)-L-tryptophan [MeSH Supplementary Concept]
- N-(4-(2-pyridyl)(1,3-thiazol-2-yl))-2-(2,4,6-trimethylphenoxy)acetamide [MeSH Supplementary Concept]
- N-benzylcinnamide [MeSH Supplementary Concept]
- NSC117079 [MeSH Supplementary Concept]
- NSC45586 [MeSH Supplementary Concept]
- P110 peptide [MeSH Supplementary Concept]
- R-7050 [MeSH Supplementary Concept]
- RTL342M protein, mouse [MeSH Supplementary Concept]
- Tat-NR2B9c [MeSH Supplementary Concept]
- Tiagabine [MeSH Descriptor]
- URMC-099 [MeSH Supplementary Concept]
- V-13,670 [MeSH Supplementary Concept]
- VCE-003 [MeSH Supplementary Concept]
- Wld(S) protein, drosophila [MeSH Supplementary Concept]
- XY99-5038 [MeSH Supplementary Concept]
- abacopterin E [MeSH Supplementary Concept]
- ac-cel compound [MeSH Supplementary Concept]
- androst-3,5,6-triol [MeSH Supplementary Concept]
- bakkenolide H [MeSH Supplementary Concept]
- casuarinine H [MeSH Supplementary Concept]
- cintrofin peptide [MeSH Supplementary Concept]
- commiterpene A [MeSH Supplementary Concept]
- commiterpene B [MeSH Supplementary Concept]
- commiterpene C [MeSH Supplementary Concept]
- creatine glycine ethylic ether fumarate [MeSH Supplementary Concept]
- ethyl 5-amino-2-methyl-6,7,8,9-tetrahydrobenzo(b)(1,8)naphthyridine-3-carboxylate [MeSH Supplementary Concept]
- gua lou gui zhi [MeSH Supplementary Concept]
- huangbai [MeSH Supplementary Concept]
- hydroperoxide isomerase [MeSH Supplementary Concept]
- lauroylethanolamide [MeSH Supplementary Concept]
- levochromakalim [MeSH Supplementary Concept]
- linoleoyl ethanolamide [MeSH Supplementary Concept]
- longistyline A [MeSH Supplementary Concept]
- lycosprenine [MeSH Supplementary Concept]
- mimengoside H [MeSH Supplementary Concept]
- mimengoside I [MeSH Supplementary Concept]
- nalmefene [MeSH Supplementary Concept]
- palmyrolide A [MeSH Supplementary Concept]
- parthenocissin A [MeSH Supplementary Concept]
- phenylalanyl-prolyl-leucyl-prolyl-alaninamide [MeSH Supplementary Concept]
- tacrine-8-hydroxyquinoline [MeSH Supplementary Concept]
- valerilactone A [MeSH Supplementary Concept]
- valerilactone B [MeSH Supplementary Concept]
Record concept(s)
- neuroprotective agents [MeSH concept]
- neuroprotective effect [MeSH concept]
See also (suggested by CISMeF)
- Neuroprotection [MeSH Descriptor]
Semantic type(s)
- Pharmacologic Substance [UMLS semantic type]
Substance(s)
- (3-aminopropyl)(n-butyl)phosphinic acid [MeSH Supplementary Concept]
- 1-amino-1,3-dicarboxycyclopentane [MeSH Supplementary Concept]
- 1-aminocyclopropane-1-carboxylic acid [MeSH Supplementary Concept]
- 3-aminobenzamide [MeSH Supplementary Concept]
- 3-n-butylphthalide [MeSH Supplementary Concept]
- 4-carboxy-3-hydroxyphenylglycine [MeSH Supplementary Concept]
- 4-methylcatechol [MeSH Supplementary Concept]
- 5-amino-7-(2-phenylethyl)-2-(2-furyl)pyrazolo(4,3-e)-1,2,4-triazolo(1,5-c)pyrimidine [MeSH Supplementary Concept]
- 5-imino-1,2,4-thiadiazole VP1.14 [MeSH Supplementary Concept]
- 6-(1H-imidazol-1-yl)-7-nitro-2,3(1H,4H)-quinoxalinedione [MeSH Supplementary Concept]
- 7-((1-alkylpiperidin-3-yl)methoxy)coumarin [MeSH Supplementary Concept]
- 7-chlorokynurenic acid [MeSH Supplementary Concept]
- 7-nitroindazole [MeSH Supplementary Concept]
- 8-((4-chlorophenyl)thio)cyclic-3',5'-AMP [MeSH Supplementary Concept]
- ACTH (4-7), Pro-Gly-Pro- [MeSH Supplementary Concept]
- AM 36 [MeSH Supplementary Concept]
- Cilostazol [MeSH Descriptor]
- DJ-1 based peptide, ND-13 [MeSH Supplementary Concept]
- DRalpha1-MOG-35-55 [MeSH Supplementary Concept]
- Edaravone [MeSH Descriptor]
- GYKI 52466 [MeSH Supplementary Concept]
- H290-51 [MeSH Supplementary Concept]
- HM01 [MeSH Supplementary Concept]
- HU 211 [MeSH Supplementary Concept]
- N-(1-methyl-2-phenylethyl)adenosine [MeSH Supplementary Concept]
- N-(3-propylcarbamoyloxirane-2-carbonyl)-isoleucyl-proline [MeSH Supplementary Concept]
- RS 5186 [MeSH Supplementary Concept]
- Rivastigmine [MeSH Descriptor]
- S-nitrosoglutathione [MeSH Descriptor]
- U 74389F [MeSH Supplementary Concept]
- U 78517F [MeSH Supplementary Concept]
- almitrine, raubasine drug combination [MeSH Supplementary Concept]
- aptiganel [MeSH Supplementary Concept]
- astressin [MeSH Supplementary Concept]
- benzyloxycarbonylvalyl-alanyl-aspartyl fluoromethyl ketone [MeSH Supplementary Concept]
- cerebrolysin [MeSH Supplementary Concept]
- chlormethiazole [MeSH Descriptor]
- dextrorphan [MeSH Descriptor]
- dizocilpine maleate [MeSH Descriptor]
- ebselen [MeSH Supplementary Concept]
- eliprodil [MeSH Supplementary Concept]
- emopag [MeSH Supplementary Concept]
- enadoline [MeSH Supplementary Concept]
- epigallocatechin gallate [MeSH Supplementary Concept]
- ethyl phenylacetyl-Pro-Gly [MeSH Supplementary Concept]
- ethylisopropylamiloride [MeSH Supplementary Concept]
- fructose-1,6-diphosphate [MeSH Supplementary Concept]
- gacyclidine [MeSH Supplementary Concept]
- huperzine A [MeSH Supplementary Concept]
- isospaglumic acid [MeSH Supplementary Concept]
- linopirdine [MeSH Supplementary Concept]
- lubeluzole [MeSH Supplementary Concept]
- meclofenoxate [MeSH Descriptor]
- mesedin [MeSH Supplementary Concept]
- methylprednisolone [MeSH Descriptor]
- methylprednisolone hemisuccinate [MeSH Descriptor]
- nefiracetam [MeSH Supplementary Concept]
- neurotrophin 4 [MeSH Supplementary Concept]
- neurotrophin 5 [MeSH Supplementary Concept]
- nitroxyl [MeSH Supplementary Concept]
- nizofenone [MeSH Supplementary Concept]
- otaplimastat [MeSH Supplementary Concept]
- phenyl-N-tert-butylnitrone [MeSH Supplementary Concept]
- piracetam [MeSH Descriptor]
- propentofylline [MeSH Supplementary Concept]
- rasagiline [MeSH Supplementary Concept]
- remacemide [MeSH Supplementary Concept]
- riluzole [MeSH Descriptor]
- rimcazole [MeSH Supplementary Concept]
- selegiline [MeSH Descriptor]
- sipatrigine [MeSH Supplementary Concept]
- tempol [MeSH Supplementary Concept]
- tenocyclidine [MeSH Supplementary Concept]
- tirilazad [MeSH Supplementary Concept]
- tricyclic pyrones [MeSH Supplementary Concept]
- vasoactive intestinal peptide [MeSH Descriptor]
- vinpocetine [MeSH Supplementary Concept]
- ziconotide [MeSH Supplementary Concept]
UMLS correspondences (same concept)
- Neuroprotective Agent [NCIt concept]

Keyword's position in hierarchy(ies) :

Main resources

You can consult :

recommendations
documents concerning education
documents for patients