Tiagabine - CISMeF

Preferred Label : Tiagabine;

MeSH definition : A nipecotic acid derivative that acts as a GABA uptake inhibitor and anticonvulsant agent. It is used in the treatment of EPILEPSY, for refractory PARTIAL SEIZURES.;

MeSH synonym : N-(4,4-di(3-Methylthien-2-yl)but-3-enyl)nipecotic acid;

MeSH hyponym : NO-329; (R)-(4,4-bis(3-Methyl-2-thienyl)-3-butenyl)-3-piperidinecarboxylic acid, Hydrochloride; NO-328;

MeSH CAS label : 3-Piperidinecarboxylic acid, 1-(4,4-bis(3-methyl-2-thienyl)-3-buten-1-yl)-, (3R)-;

MeSH Related Number : 115103-54-3 (Tiagabine); 115103-55-4 ((S)-isomer); DQH6T6D8OY;

Wikipedia link : https://en.wikipedia.org/wiki/Tiagabine;

UNII : Z80I64HMNP;

Details

Origin ID

D000078308;

UMLS CUI

C0068897;

ATC code(s)
- tiagabine [ATC Code]
Allowable qualifiers
- administration and dosage [MeSH Qualifier]
- adverse effects [MeSH Qualifier]
- agonists [MeSH Qualifier]
- analogs and derivatives [MeSH Qualifier]
- analysis [MeSH Qualifier]
- antagonists and inhibitors [MeSH Qualifier]
- blood [MeSH Qualifier]
- cerebrospinal fluid [MeSH Qualifier]
- chemical synthesis [MeSH Qualifier]
- chemistry [MeSH Qualifier]
- classification [MeSH Qualifier]
- economics [MeSH Qualifier]
- history [MeSH Qualifier]
- immunology [MeSH Qualifier]
- isolation and purification [MeSH Qualifier]
- metabolism [MeSH Qualifier]
- pharmacokinetics [MeSH Qualifier]
- pharmacology [MeSH Qualifier]
- poisoning [MeSH Qualifier]
- radiation effects [MeSH Qualifier]
- standards [MeSH Qualifier]
- supply and distribution [MeSH Qualifier]
- therapeutic use [MeSH Qualifier]
- toxicity [MeSH Qualifier]
- urine [MeSH Qualifier]
False automatic mappings
- Guyana [NCIt concept]
MeSH indexing information
- neuroprotective agents [MeSH Descriptor]
Pharmacological action(s)
- GABA uptake inhibitors [MeSH Descriptor]
- anticonvulsants [MeSH Descriptor]
Record concept(s)
- NO 328 [MeSH concept]
- NO 329 [MeSH concept]
- Tiagabine Hydrochloride [MeSH concept]
- gabitril [MeSH concept]
- tiagabine [MeSH concept]
- tiagabine, (S)-isomer [MeSH concept]
See also inter- (CISMeF)
- Product containing tiagabine (medicinal product) [SNOMED CT concept]
Semantic type(s)
- Organic Chemical [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
Validated automatic mappings to BTNT
- Tiagabine Hydrochloride [NCIt concept]
- Tiagabine hydrochloride (substance) [SNOMED CT concept]
- tiagabine [ATC Code]

Keyword's position in hierarchy(ies) :

Main resources

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