selegiline - CISMeF

Preferred Label : selegiline;

MeSH definition : A selective, irreversible inhibitor of Type B monoamine oxidase. It is used in newly diagnosed patients with Parkinson's disease. It may slow progression of the clinical disease and delay the requirement for levodopa therapy. It also may be given with levodopa upon onset of disability. (From AMA Drug Evaluations Annual, 1994, p385) The compound without isomeric designation is Deprenyl.; A selective, irreversible inhibitor of Type B monoamine oxidase that is used for the treatment of newly diagnosed patients with PARKINSON DISEASE, and for the treatment of depressive disorders. The compound without isomeric designation is Deprenyl.;

MeSH synonym : selegyline; l-deprenyl; selegiline, (r)-isomer;

CISMeF synonym : 2079-54-1 (Selegiline hydrochloride, (R)-Isomer); Bristol-Myers squibb brand of selegiline; bristol myers squibb brand of selegiline; valeant brand of selegiline; selegiline valeant brand; hydrochloride, selegiline;

MeSH hyponym : eldepryl; yumex; selegiline hydrochloride, (R,S)-Isomer; deprenyl; E-250; Selegiline Hydrochloride, (R)-Isomer; emsam; zelapar; selegiline hydrochloride, (S)-Isomer; Jumex; Humex; E 250; E250; Selegiline Hydrochloride;

Related MeSH term : selegiline, (S)-Isomer; selegiline, (R,S)-Isomer; Deprenalin; Deprenil;

MeSH CAS label : benzeneethanamine, N,alpha-dimethyl-N-2-propynyl-, (R)-;

MeSH Related Number : selegiline hydrochloride, (R,S)-Isomer; selegiline hydrochloride, (S)-Isomer; selegiline, (R,S)-Isomer; selegiline, (S)-Isomer; selegiline hydrochloride, (R)-Isomer; 1205-70-5 (( -)-isomer, HCl); 14611-52-0 (HCl); 2079-54-1 (deprenyl.HCl); 2323-36-6 (cpd without isomeric designation; 4528-51-2 ((S)-isomer); 4528-52-3 ((S)-isomer, HCl); 4530-70-5 (( -)-isomer); deprenyl); 6W731X367Q; 14611-51-9;

Registry Number MeSH : 14611-51-9;

Related CAS MeSH : 1205-70-5 (Selegiline hydrochloride, (R,S)-Isomer); 4528-52-3 (Selegiline hydrochloride, (S)-Isomer); 4530-70-5 (Selegiline, (R,S)-Isomer); 4528-51-2 (Selegiline, (S)-Isomer); 6W731X367Q (Selegiline hydrochloride, (R)-Isomer);

Wikipedia link : https://en.wikipedia.org/wiki/E250;

Is substance : O;

UNII : 2K1V7GP655;

Details

Origin ID

D012642;

UMLS CUI

C0036579;

ATC code(s)
- selegiline [ATC Code]
ATC code(s)
- selegiline [ATC Code]
Allowable qualifiers
- administration and dosage [MeSH Qualifier]
- adverse effects [MeSH Qualifier]
- agonists [MeSH Qualifier]
- analogs and derivatives [MeSH Qualifier]
- analysis [MeSH Qualifier]
- antagonists and inhibitors [MeSH Qualifier]
- blood [MeSH Qualifier]
- cerebrospinal fluid [MeSH Qualifier]
- chemical synthesis [MeSH Qualifier]
- chemistry [MeSH Qualifier]
- classification [MeSH Qualifier]
- contraindications [MeSH Qualifier]
- economics [MeSH Qualifier]
- history [MeSH Qualifier]
- immunology [MeSH Qualifier]
- isolation and purification [MeSH Qualifier]
- metabolism [MeSH Qualifier]
- pharmacokinetics [MeSH Qualifier]
- pharmacology [MeSH Qualifier]
- poisoning [MeSH Qualifier]
- radiation effects [MeSH Qualifier]
- standards [MeSH Qualifier]
- supply and distribution [MeSH Qualifier]
- therapeutic use [MeSH Qualifier]
- toxicity [MeSH Qualifier]
- urine [MeSH Qualifier]
Automatic exact mappings (from CISMeF team)
- Deprenalin [ICHI extension code]
- Deprenyl [ICHI extension code]
CISMeF manual mappings
- Selegiline adverse reaction (disorder) [SNOMED CT concept]
- Selegiline measurement (procedure) [SNOMED CT concept]
- Selegiline poisoning (disorder) [SNOMED CT concept]
Currated CISMeF NLP mapping
- Selegiline [ICD-11 Extension code]
- Selegiline [LOINC component]
- Selegiline [ICHI extension code]
- Selegiline [SMS substance]
- Selegiline [NCIt concept]
- Selegiline (substance) [SNOMED CT concept]
Pharmacological action(s)
- antidepressive agents [MeSH Descriptor]
- antiparkinson agents [MeSH Descriptor]
- monoamine oxidase inhibitors [MeSH Descriptor]
- neuroprotective agents [MeSH Descriptor]
Record concept(s)
- E-250 [MeSH concept]
- Selegiline Hydrochloride, (R)-Isomer [MeSH concept]
- deprenyl [MeSH concept]
- eldepryl [MeSH concept]
- emsam [MeSH concept]
- selegiline [MeSH concept]
- selegiline hydrochloride, (R,S)-Isomer [MeSH concept]
- selegiline hydrochloride, (S)-Isomer [MeSH concept]
- selegiline, (R,S)-Isomer [MeSH concept]
- selegiline, (S)-Isomer [MeSH concept]
- yumex [MeSH concept]
- zelapar [MeSH concept]
Related MeSH Supplementary Concept(s)
- 4-fluorodeprenyl [MeSH Supplementary Concept]
- N-(1-fluoro-3-phenylpropan-2-yl)-N-methylprop-2-yn-1-amine [MeSH Supplementary Concept]
- N-Methyl,N-propargyphenylethylamine [MeSH Supplementary Concept]
- deprenyl-N-oxide [MeSH Supplementary Concept]
- fluorodeprenyl [MeSH Supplementary Concept]
- p-fluoro-L-deprenyl [MeSH Supplementary Concept]
- selegiline-N-oxide [MeSH Supplementary Concept]
See also inter- (CISMeF)
- Deprenalin [ICD-11 Extension code]
- Deprenyl [ICD-11 Extension code]
- Product containing selegiline (medicinal product) [SNOMED CT concept]
Semantic type(s)
- Organic Chemical [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
UMLS correspondences (same concept)
- Product containing selegiline (medicinal product) [SNOMED CT concept]
- Selegiline [ICD-11 Extension code]
- Selegiline [NCIt concept]
- Selegiline [LOINC component]
- Selegiline (substance) [SNOMED CT concept]
- selegiline [ATC Code]

Keyword's position in hierarchy(ies) :

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