Preferred Label : dizocilpine maleate;
MeSH definition : A potent noncompetitive antagonist of the NMDA receptor (RECEPTORS, N-METHYL-D-ASPARTATE)
used mainly as a research tool. The drug has been considered for the wide variety
of neurodegenerative conditions or disorders in which NMDA receptors may play an important
role. Its use has been primarily limited to animal and tissue experiments because
of its psychotropic effects.;
CISMeF synonym : ( )-10,11-dihydro-5-methyl-5h-dibenzo[a,d]cyclohepten-5,10-diyldiammonium maleate; 77086-21-6 (Dizocilpine);
MeSH hyponym : MK-801; dizocilpine; MK 801; MK801;
MeSH CAS label : 5H-Dibenzo(a,d)cyclohepten-5,10-imine, 10,11-dihydro-5-methyl-, (5S)-, (Z)-2-butenedioate
(1:1);
MeSH Related Number : dizocilpine; 77086-21-6 (parent); 77086-22-7 (Dizocilpine maleate); 7PY8KH681I;
Libelles Related CAS CISMeF : dizocilpine;
Registry Number MeSH : 77086-22-7;
Related CAS MeSH : 7PY8KH681I (Dizocilpine);
MeSH annotation : DF: note short X;
Wikipedia link : https://en.wikipedia.org/wiki/Dizocilpine;
Codes EINECS : 278-614-5;
Is substance : O;
UNII : 6LR8C1B66Q;
InChIKey : QLTXKCWMEZIHBJ-PJGJYSAQSA-N;
Origin ID : D016291;
UMLS CUI : C0079246;
Allowable qualifiers
- Automatic exact mappings (from CISMeF team)
- CISMeF manual mappings
- Pharmacological action(s)
- Record concept(s)
- Related MeSH Supplementary Concept(s)
- Semantic type(s)
- UMLS correspondences (same concept)
A potent noncompetitive antagonist of the NMDA receptor (RECEPTORS, N-METHYL-D-ASPARTATE)
used mainly as a research tool. The drug has been considered for the wide variety
of neurodegenerative conditions or disorders in which NMDA receptors may play an important
role. Its use has been primarily limited to animal and tissue experiments because
of its psychotropic effects.
