chlormethiazole

Preferred Label : chlormethiazole;

MeSH definition : A sedative and anticonvulsant often used in the treatment of alcohol withdrawal. Chlormethiazole has also been proposed as a neuroprotective agent. The mechanism of its therapeutic activity is not entirely clear, but it does potentiate GAMMA-AMINOBUTYRIC ACID receptors response and it may also affect glycine receptors.;

MeSH synonym : clomethiazole;

MeSH hyponym : distraneurin;

MeSH CAS label : thiazole, 5-(2-chloroethyl)-4-methyl-;

MeSH Related Number : 533-45-9 (Chlormethiazole);

Registry Number MeSH : 533-45-9;

Wikipedia link : https://en.wikipedia.org/wiki/Chlormethiazole;

Codes EINECS : 208-565-7;

Is substance : O;

UNII : 0C5DBZ19HV;

InChIKey : PCLITLDOTJTVDJ-UHFFFAOYSA-N;

Details

Origin ID

D002719;

UMLS CUI

C0008221;

ATC code(s)
- clomethiazole [ATC Code]
- clomethiazole, combinations [ATC Code]
Allowable qualifiers
- administration and dosage [MeSH Qualifier]
- adverse effects [MeSH Qualifier]
- agonists [MeSH Qualifier]
- analogs and derivatives [MeSH Qualifier]
- analysis [MeSH Qualifier]
- antagonists and inhibitors [MeSH Qualifier]
- blood [MeSH Qualifier]
- cerebrospinal fluid [MeSH Qualifier]
- chemical synthesis [MeSH Qualifier]
- chemistry [MeSH Qualifier]
- classification [MeSH Qualifier]
- contraindications [MeSH Qualifier]
- economics [MeSH Qualifier]
- history [MeSH Qualifier]
- immunology [MeSH Qualifier]
- isolation and purification [MeSH Qualifier]
- metabolism [MeSH Qualifier]
- pharmacokinetics [MeSH Qualifier]
- pharmacology [MeSH Qualifier]
- poisoning [MeSH Qualifier]
- radiation effects [MeSH Qualifier]
- standards [MeSH Qualifier]
- supply and distribution [MeSH Qualifier]
- therapeutic use [MeSH Qualifier]
- toxicity [MeSH Qualifier]
- urine [MeSH Qualifier]
Automatic exact mappings (from CISMeF team)
- Chlormethiazole [ICHI extension code]
- Clomethiazole [ICHI extension code]
CISMeF manual mappings
- Chlormethiazole poisoning (disorder) [SNOMED CT concept]
- chlormethiazole [Substance BNPC]
Currated CISMeF NLP mapping
- Chlormethiazole [ICD-11 Extension code]
- Chlormethiazole (substance) [Inactive SNOMED CT concept]
- Clomethiazole [ICD-11 Extension code]
- Clomethiazole [LOINC component]
- Clomethiazole [NCIt concept]
- Clomethiazole (substance) [SNOMED CT concept]
Pharmacological action(s)
- GABA modulators [MeSH Descriptor]
- anticonvulsants [MeSH Descriptor]
- hypnotics and sedatives [MeSH Descriptor]
- neuroprotective agents [MeSH Descriptor]
Record concept(s)
- chlormethiazole [MeSH concept]
- distraneurin [MeSH concept]
Related MeSH Supplementary Concept(s)
- 5-(1-hydroxyethyl)-4-methylthiazole [MeSH Supplementary Concept]
- 5-acetyl-4-methylthiazole [MeSH Supplementary Concept]
- clomethiazole edisylate [MeSH Supplementary Concept]
See also inter- (CISMeF)
- Product containing clomethiazole (medicinal product) [SNOMED CT concept]
Semantic type(s)
- Organic Chemical [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
UMLS correspondences (same concept)
- Chlormethiazole (substance) [Inactive SNOMED CT concept]
- Clomethiazole [ICD-11 Extension code]
- Clomethiazole [LOINC component]
- Clomethiazole [NCIt concept]
- Clomethiazole (substance) [SNOMED CT concept]
- Product containing clomethiazole (medicinal product) [SNOMED CT concept]
- chlormethiazole [Substance BNPC]
- clomethiazole [ATC Code]
Validated automatic mappings to BTNT
- clomethiazole [ATC Code]

Keyword's position in hierarchy(ies) :

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