dna repair - CISMeF

Preferred Label : dna repair;

MeSH definition : The reconstruction of a continuous two-stranded DNA molecule without mismatch from a molecule which contained damaged regions. The major repair mechanisms are excision repair, in which defective regions in one strand are excised and resynthesized using the complementary base pairing information in the intact strand; photoreactivation repair, in which the lethal and mutagenic effects of ultraviolet light are eliminated; and post-replication repair, in which the primary lesions are not repaired, but the gaps in one daughter duplex are filled in by incorporation of portions of the other (undamaged) daughter duplex. Excision repair and post-replication repair are sometimes referred to as dark repair because they do not require light.; The removal of DNA LESIONS and/or restoration of intact DNA strands without BASE PAIR MISMATCHES, intrastrand or interstrand crosslinks, or discontinuities in the DNA sugar-phosphate backbones.;

MeSH hyponym : excision repair; base excision repair; nucleotide excision repair; Excision Repairs; Repair, Excision; Excision Repair, Nucleotide; Nucleotide Excision Repairs; Base Excision Repairs; Excision Repair, Base; Repair, Base Excision; Repairs, Base Excision;

MeSH annotation : coord IM with specific DNA (IM);

Wikipedia link : https://en.wikipedia.org/wiki/Base excision repair;

Details

Origin ID

D004260;

UMLS CUI

C0012899;

Allowable qualifiers
- drug effects [MeSH Qualifier]
- genetics [MeSH Qualifier]
- immunology [MeSH Qualifier]
- physiology [MeSH Qualifier]
- radiation effects [MeSH Qualifier]
Automatic exact mappings (from CISMeF team)
- Base Excision Repair [NCIt concept]
- Base Excision Repair Pathway [NCIt concept]
- DNA repair [GO term]
- Excision Repair [NCIt concept]
- Nucleotide Excision Repair [NCIt concept]
- Nucleotide Excision Repair Pathway [NCIt concept]
- base-excision repair [GO term]
- nucleotide-excision repair [GO term]
Currated CISMeF NLP mapping
- DNA Repair [NCIt concept]
- Deoxyribonucleic acid repair (finding) [SNOMED CT concept]
- dna repair [SNOMED Notion]
Indexing information
- 3'-phosphoglycoaldehyde diesterase [MeSH Supplementary Concept]
- 3-methyladenine-DNA glycosylase [MeSH Supplementary Concept]
- ALKBH2 protein, human [MeSH Supplementary Concept]
- ALKBH3 protein, human [MeSH Supplementary Concept]
- ALKBH8 protein, mouse [MeSH Supplementary Concept]
- APEX1 protein, human [MeSH Supplementary Concept]
- APTX protein, human [MeSH Supplementary Concept]
- Apex1 protein, mouse [MeSH Supplementary Concept]
- Apn1 protein, S cerevisiae [MeSH Supplementary Concept]
- Apn2 protein, S pombe [MeSH Supplementary Concept]
- BABAM1 protein, human [MeSH Supplementary Concept]
- BRC-2 protein, C elegans [MeSH Supplementary Concept]
- BRCC36A protein, arabidopsis [MeSH Supplementary Concept]
- BRCC36B protein, arabidopsis [MeSH Supplementary Concept]
- CYCSP39 protein, human [MeSH Supplementary Concept]
- Cti1 protein, S pombe [MeSH Supplementary Concept]
- DCLRE1A protein, human [MeSH Supplementary Concept]
- DCLRE1C protein, human [MeSH Supplementary Concept]
- DNA alkyltransferase [MeSH Supplementary Concept]
- DNA excision repair protein ERCC-5 [MeSH Supplementary Concept]
- DNA polymerase X [MeSH Supplementary Concept]
- DNA repair protein, 230-kDa, human [MeSH Supplementary Concept]
- DNA-3-methyladenine glycosidase II [MeSH Supplementary Concept]
- Dclre1c protein, mouse [MeSH Supplementary Concept]
- ERCC1 protein, human [MeSH Supplementary Concept]
- ERCC6 protein, human [MeSH Supplementary Concept]
- ERCC6L2 protein, human [MeSH Supplementary Concept]
- Ercc1 protein, arabidopsis [MeSH Supplementary Concept]
- Ercc1 protein, mouse [MeSH Supplementary Concept]
- FAN1 protein, human [MeSH Supplementary Concept]
- G-T mismatch-binding protein [MeSH Supplementary Concept]
- GTF2H2 protein, arabidopsis [MeSH Supplementary Concept]
- GTF2H5 protein, human [MeSH Supplementary Concept]
- HSM3 protein, S cerevisiae [MeSH Supplementary Concept]
- HexA protein, bacteria [MeSH Supplementary Concept]
- ImpC protein, bacteria [MeSH Supplementary Concept]
- Irc20 protein, S cerevisiae [MeSH Supplementary Concept]
- Ku80 protein, arabidopsis [MeSH Supplementary Concept]
- LIF1 protein, S cerevisiae [MeSH Supplementary Concept]
- MEI-9 protein, Drosophila [MeSH Supplementary Concept]
- MEI1 protein, arabidopsis [MeSH Supplementary Concept]
- MHF1 protein, S cerevisiae [MeSH Supplementary Concept]
- MHF2 protein, S cerevisiae [MeSH Supplementary Concept]
- MLH1 protein, arabidopsis [MeSH Supplementary Concept]
- MLH1 protein, human [MeSH Supplementary Concept]
- MLH2 protein, S cerevisiae [MeSH Supplementary Concept]
- MLH3 protein, S cerevisiae [MeSH Supplementary Concept]
- MLH3 protein, human [MeSH Supplementary Concept]
- MMS19 protein, human [MeSH Supplementary Concept]
- MMS2 protein, S cerevisiae [MeSH Supplementary Concept]
- MMS22L protein, human [MeSH Supplementary Concept]
- MMS4 protein, S cerevisiae [MeSH Supplementary Concept]
- MND1 protein, arabidopsis [MeSH Supplementary Concept]
- MSH2 protein, arabidopsis [MeSH Supplementary Concept]
- MSH2 protein, trypanosoma cruzi [MeSH Supplementary Concept]
- MSH3 protein, arabidopsis [MeSH Supplementary Concept]
- MSH4 protein, human [MeSH Supplementary Concept]
- MSH6 protein, arabidopsis [MeSH Supplementary Concept]
- MSH7 protein, arabidopsis [MeSH Supplementary Concept]
- MSL1 protein, human [MeSH Supplementary Concept]
- MUS-23 protein, neurospora crassa [MeSH Supplementary Concept]
- MUS11 protein, neurospora crassa [MeSH Supplementary Concept]
- MUS312 protein, drosophila [MeSH Supplementary Concept]
- MUS81 protein, arabidopsis [MeSH Supplementary Concept]
- Mag1 protein, S pombe [MeSH Supplementary Concept]
- Mbd4 protein, mouse [MeSH Supplementary Concept]
- Mei-P22 protein, drosophila [MeSH Supplementary Concept]
- Mlh1 protein, rat [MeSH Supplementary Concept]
- Mlh3 protein, mouse [MeSH Supplementary Concept]
- Mms1 protein, S pombe [MeSH Supplementary Concept]
- MmsA protein, streptococcus pneumoniae [MeSH Supplementary Concept]
- Mre11 protein, S pombe [MeSH Supplementary Concept]
- Mre11 protein, arabidopsis [MeSH Supplementary Concept]
- Msh3 protein, mouse [MeSH Supplementary Concept]
- Msh4 protein, mouse [MeSH Supplementary Concept]
- Msh6 protein, mouse [MeSH Supplementary Concept]
- Mus-18 protein, neurospora crassa [MeSH Supplementary Concept]
- Mus-8 protein, neurospora crassa [MeSH Supplementary Concept]
- MutK protein, vibrio cholerae [MeSH Supplementary Concept]
- MutLalpha protein, human [MeSH Supplementary Concept]
- NBN protein, Xenopus [MeSH Supplementary Concept]
- NEJ1 protein, S cerevisiae [MeSH Supplementary Concept]
- NHEJ1 protein, human [MeSH Supplementary Concept]
- NSE1 protein, S cerevisiae [MeSH Supplementary Concept]
- NSE4 protein, S cerevisiae [MeSH Supplementary Concept]
- NSMCE2 protein, human [MeSH Supplementary Concept]
- NTH protein, E coli [MeSH Supplementary Concept]
- Nhej1 protein, rat [MeSH Supplementary Concept]
- Nse1 protein, S pombe [MeSH Supplementary Concept]
- Nse2 protein, S pombe [MeSH Supplementary Concept]
- Nse4 protein, S pombe [MeSH Supplementary Concept]
- Nth1 protein, S pombe [MeSH Supplementary Concept]
- O(2)-methylthymine-DNA glycosidase [MeSH Supplementary Concept]
- O(4)-methylthymine-DNA methyltransferase [MeSH Supplementary Concept]
- Ogg1 protein, S cerevisiae [MeSH Supplementary Concept]
- PARP4 protein, human [MeSH Supplementary Concept]
- PBY1 protein, S cerevisiae [MeSH Supplementary Concept]
- PMS1 protein, S cerevisiae [MeSH Supplementary Concept]
- PMS1 protein, arabidopsis [MeSH Supplementary Concept]
- PMS1 protein, human [MeSH Supplementary Concept]
- PMS2 protein, human [MeSH Supplementary Concept]
- PSO2 protein, S cerevisiae [MeSH Supplementary Concept]
- Pms2 protein, mouse [MeSH Supplementary Concept]
- Psy2 protein, S cerevisiae [MeSH Supplementary Concept]
- RAD1 protein, S cerevisiae [MeSH Supplementary Concept]
- RAD16 protein, S pombe [MeSH Supplementary Concept]
- RAD17 protein, arabidopsis [MeSH Supplementary Concept]
- RAD2 protein, S cerevisiae [MeSH Supplementary Concept]
- RAD23A protein, human [MeSH Supplementary Concept]
- RAD31 protein, S pombe [MeSH Supplementary Concept]
- RAD4 protein, arabidopsis [MeSH Supplementary Concept]
- RAD51 protein, leishmania major [MeSH Supplementary Concept]
- RAD51B protein, arabidopsis [MeSH Supplementary Concept]
- RAD51D protein, arabidopsis [MeSH Supplementary Concept]
- RAD54L protein, human [MeSH Supplementary Concept]
- RAD55 protein, S cerevisiae [MeSH Supplementary Concept]
- RAD59 protein, S cerevisiae [MeSH Supplementary Concept]
- REC2 protein, ustilago maydis [MeSH Supplementary Concept]
- RHP23 protein, S pombe [MeSH Supplementary Concept]
- RHP51 protein, S pombe [MeSH Supplementary Concept]
- RHP55 protein, S pombe [MeSH Supplementary Concept]
- RMI1 protein, arabidopsis [MeSH Supplementary Concept]
- RMI2 protein, Arabidopsis [MeSH Supplementary Concept]
- RNF146 protein, human [MeSH Supplementary Concept]
- RRM2B protein, human [MeSH Supplementary Concept]
- RSC1 protein, S cerevisiae [MeSH Supplementary Concept]
- Rad11 protein, S pombe [MeSH Supplementary Concept]
- Rad18 protein, rat [MeSH Supplementary Concept]
- Rad21 protein, S pombe [MeSH Supplementary Concept]
- Rad21 protein, xenopus [MeSH Supplementary Concept]
- Rad22B protein, S pombe [MeSH Supplementary Concept]
- Rad23a protein, mouse [MeSH Supplementary Concept]
- Rad23b protein, mouse [MeSH Supplementary Concept]
- Rad30 protein [MeSH Supplementary Concept]
- Rad4 protein, S cerevisiae [MeSH Supplementary Concept]
- Rad50 protein, S pombe [MeSH Supplementary Concept]
- Rad50 protein, mouse [MeSH Supplementary Concept]
- Rad60 protein, S pombe [MeSH Supplementary Concept]
- RadA protein, E coli [MeSH Supplementary Concept]
- RadA protein, bacteria [MeSH Supplementary Concept]
- RdgB protein, E coli [MeSH Supplementary Concept]
- RecJ protein, E coli [MeSH Supplementary Concept]
- Rhp41 protein, S pombe [MeSH Supplementary Concept]
- Rhp57 protein, S pombe [MeSH Supplementary Concept]
- Rrm2b protein, mouse [MeSH Supplementary Concept]
- Rrp1 protein, S pombe [MeSH Supplementary Concept]
- Rrp2 protein, S pombe [MeSH Supplementary Concept]
- RuvB protein, bacteria [MeSH Supplementary Concept]
- SETMAR protein, human [MeSH Supplementary Concept]
- SFR1 protein, human [MeSH Supplementary Concept]
- SLX1 protein, S cerevisiae [MeSH Supplementary Concept]
- SLX1 protein, human [MeSH Supplementary Concept]
- SPF45 protein, drosophila [MeSH Supplementary Concept]
- SPO11-2 protein, arabidopsis [MeSH Supplementary Concept]
- SSN2 protein, arabidopsis [MeSH Supplementary Concept]
- SWI10 protein, S pombe [MeSH Supplementary Concept]
- Shu1 protein, S cerevisiae [MeSH Supplementary Concept]
- Swi5 protein, S pombe [MeSH Supplementary Concept]
- Swi5 protein, human [MeSH Supplementary Concept]
- TENT4A protein, human [MeSH Supplementary Concept]
- Tex15 protein, mouse [MeSH Supplementary Concept]
- Tim1 protein, xenopus [MeSH Supplementary Concept]
- UVH6 protein, arabidopsis [MeSH Supplementary Concept]
- UvrB protein, E coli [MeSH Supplementary Concept]
- UvsH protein, aspergillus nidulans [MeSH Supplementary Concept]
- WRN protein, rat [MeSH Supplementary Concept]
- WSS1 protein, S cerevisiae [MeSH Supplementary Concept]
- X-ray repair cross complementing protein 3 [MeSH Supplementary Concept]
- XAB2 protein, human [MeSH Supplementary Concept]
- XAB2 protein, mouse [MeSH Supplementary Concept]
- XLF protein, mouse [MeSH Supplementary Concept]
- XPA protein, rat [MeSH Supplementary Concept]
- XPB1 protein, arabidopsis [MeSH Supplementary Concept]
- XPB2 protein, arabidopsis [MeSH Supplementary Concept]
- XPBC-ERCC-3 protein [MeSH Supplementary Concept]
- XPC protein, human [MeSH Supplementary Concept]
- XPC protein, rat [MeSH Supplementary Concept]
- XRCC2 protein, arabidopsis [MeSH Supplementary Concept]
- XRCC4 protein, arabidopsis [MeSH Supplementary Concept]
- XRCC4 protein, human [MeSH Supplementary Concept]
- XRCC5 protein, human [MeSH Supplementary Concept]
- XRCC8 protein, human [MeSH Supplementary Concept]
- ZTF-8 protein, C elegans [MeSH Supplementary Concept]
- alkyltransferase-like protein, E coli [MeSH Supplementary Concept]
- cho protein, E coli [MeSH Supplementary Concept]
- correxonuclease [MeSH Supplementary Concept]
- deoxynucleotide 3'-phosphatase [MeSH Supplementary Concept]
- hay protein, Drosophila [MeSH Supplementary Concept]
- impA protein, salmonella typhimurium [MeSH Supplementary Concept]
- methyl-directed mismatch repair protein, E coli [MeSH Supplementary Concept]
- mitochondrial oxidative damage endonuclease [MeSH Supplementary Concept]
- msh-2 protein, C elegans [MeSH Supplementary Concept]
- msh-6 protein, C elegans [MeSH Supplementary Concept]
- msh2 protein, S pombe [MeSH Supplementary Concept]
- mus101 protein, drosophila [MeSH Supplementary Concept]
- nbs protein, drosophila [MeSH Supplementary Concept]
- proksifein [MeSH Supplementary Concept]
- purine imidazole-ring cyclase [MeSH Supplementary Concept]
- rad1 protein, S pombe [MeSH Supplementary Concept]
- rad25 protein, S pombe [MeSH Supplementary Concept]
- rad52 protein, S pombe [MeSH Supplementary Concept]
- recJ protein, bacteria [MeSH Supplementary Concept]
- ribosomal protein P0, drosophila [MeSH Supplementary Concept]
- ring-opened-7-methylguanine DNA glycosylase [MeSH Supplementary Concept]
- scc-1 protein, C elegans [MeSH Supplementary Concept]
- spel1 protein, Drosophila [MeSH Supplementary Concept]
- spn-B protein, Drosophila [MeSH Supplementary Concept]
- spore photoproduct lyase [MeSH Supplementary Concept]
- tipin protein, xenopus [MeSH Supplementary Concept]
- uve1 protein, S pombe [MeSH Supplementary Concept]
- vsr endonuclease [MeSH Supplementary Concept]
- xeroderma pigmentosum group F protein [MeSH Supplementary Concept]
- xpc protein, mouse [MeSH Supplementary Concept]
- yicR protein, E coli [MeSH Supplementary Concept]
Record concept(s)
- DNA Damage Response [MeSH concept]
- DNA repair [MeSH concept]
Related MeSH Supplementary Concept(s)
- RAD28 protein, S cerevisiae [MeSH Supplementary Concept]
See also
- DNA Damage Tolerance [MeSH Descriptor]
- DNA-Formamidopyrimidine glycosylase [MeSH Descriptor]
- dna damage [MeSH Descriptor]
- dna repair enzymes [MeSH Descriptor]
- pyrimidine dimers [MeSH Descriptor]
- targeted gene repair [MeSH Descriptor]
Semantic type(s)
- Genetic Function [UMLS semantic type]

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