DNA Damage Tolerance

Preferred Label : DNA Damage Tolerance;

MeSH definition : Strategies that cells use to continue DNA replication when replicative DNA polymerases stall at DNA damage-blocked replication forks. These DNA damage tolerant replication mechanisms bypass the DNA DAMAGE, which may be repaired subsequently by various DNA REPAIR mechanisms.;

MeSH synonym : Postreplication Repair; DNA Damage Tolerance Pathways; Post Replication Repair; Postreplicative Repair; DNA Damage Tolerant Replication; DNA Damage Bypass Pathways; Post-Replication Repair; Post-Replication Repairs;

MeSH hyponym : Fork Reversal, Replication; Template Switching, Postreplicative; Replication Template Switching; Template Switching, Replication;

Details

Origin ID

D000097122;

UMLS CUI

C1158558;

Allowable qualifiers
- drug effects [MeSH Qualifier]
- genetics [MeSH Qualifier]
- immunology [MeSH Qualifier]
- physiology [MeSH Qualifier]
- radiation effects [MeSH Qualifier]
Currated CISMeF NLP mapping
- replication fork reversal [GO term]
Record concept(s)
- DNA Damage Tolerance [MeSH concept]
- Postreplicative Template Switching [MeSH concept]
- Replication Fork Reversal [MeSH concept]
See also
- dna repair [MeSH Descriptor]
See also inter- (CISMeF)
- postreplication repair [GO term]
Semantic type(s)
- Genetic Function [UMLS semantic type]
UMLS correspondences (same concept)
- postreplication repair [GO term]

Keyword's position in hierarchy(ies) :

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