Preferred Label : Certolizumab Pegol;
MeSH definition : A polyethylene-glycolated Fab' fragment of TUMOR NECROSIS FACTOR antibody that binds
specifically to TNF-ALPHA and neutralises it in a dose-dependent manner. It also inhibits
the production of lipopolysaccharide-induced TNF-ALPHA and IL-1 BETA and is used to
treat RHEUMATOID ARTHRITIS and PSORIATIC ARTHRITIS.;
CISMeF synonym : Certolizumab Pegols; Pegol, Certolizumab; Pegols, Certolizumab; Cimzias; CDP870s; 870, CDP; 870s, CDP; CDP 870s;
MeSH hyponym : CDP870; cimzia; CDP 870;
MeSH Related Number : 428863-50-7;
Wikipedia link : https://en.wikipedia.org/wiki/Certolizumab pegol;
Is substance : O;
UNII : UMD07X179E;
Origin ID : D000068582;
UMLS CUI : C1872109;
- ATC code(s)
- Allowable qualifiers
- Automatic exact mappings (from CISMeF team)
- Pharmacological action(s)
- Record concept(s)
- See also
- See also inter- (CISMeF)
- Semantic type(s)
- UMLS correspondences (same concept)
- Validated automatic mappings to BTNT
- Validated automatic mappings to NTBT
A polyethylene-glycolated Fab' fragment of TUMOR NECROSIS FACTOR antibody that binds
specifically to TNF-ALPHA and neutralises it in a dose-dependent manner. It also inhibits
the production of lipopolysaccharide-induced TNF-ALPHA and IL-1 BETA and is used to
treat RHEUMATOID ARTHRITIS and PSORIATIC ARTHRITIS.
https://www.has-sante.fr/jcms/p_3539114/fr/cimzia-certolizumab-pegol-biotherapies-par-voie-sous-cutanee-dans-les-maladies-inflammatoires-chroniques
2024
false
false
false
France
drug prescriptions
evaluation of the transparency committee
biological therapy
injections, subcutaneous
Certolizumab Pegol
chronic disease
---
https://www.has-sante.fr/jcms/p_3363302/fr/cimzia-certolizumab-pegol-psoriasis-en-plaques-de-l-adulte
2022
false
false
false
France
treatment outcome
insurance, health, reimbursement
psoriasis
adult
certolizumab pegol
immunosuppressive agents
injections, subcutaneous
evaluation of the transparency committee
Certolizumab Pegol
---
https://www.ansm.sante.fr/actualites/modification-des-conditions-de-prescription-et-delivrance-de-certaines-biotherapies-utilisees-dans-le-traitement-de-maladies-inflammatoires-chroniques-en-rhumatologie-gastroenterologie-dermatologie-ophtalmologie
2019
false
false
false
France
French
drug prescriptions
drug information
Adalimumab
Etanercept
golimumab
Certolizumab Pegol
anakinra
interleukin 1 receptor antagonist protein
antibodies, monoclonal
---
https://www.cochrane.org/fr/CD012893/certolizumab-pegol-pour-le-traitement-de-la-maladie-de-crohn-active
2019
false
false
false
France
United Kingdom
adult
treatment outcome
review of literature
french abstract
Certolizumab Pegol
crohn disease
---
https://www.has-sante.fr/portail/jcms/c_2908904/fr/cimzia
2019
false
true
false
false
France
certolizumab pegol
injections, subcutaneous
psoriasis
treatment outcome
adult
insurance, health, reimbursement
chronic disease
evaluation of the transparency committee
Certolizumab Pegol
---
https://www.has-sante.fr/portail/jcms/c_2908459/fr/cimzia
2019
false
false
false
false
France
Injectable Solution Dosage Form
Prefilled Syringe Dosage Form
Pre-filled Pen Syringe
treatment outcome
Certolizumab Pegol
pregnant women
arthritis, rheumatoid
spondylarthropathies
arthritis, psoriatic
psoriasis
Certolizumab Pegol
evaluation of the transparency committee
cimzia
Certolizumab Pegol
---
https://www.revmed.ch/RMS/2017/RMS-N-553/Effets-secondaires-des-traitements-biologiques
2017
false
false
false
Switzerland
French
journal article
biological therapy
Inflammatory joint disease
Infliximab
antirheumatic agents
gastrointestinal agents
Etanercept
Adalimumab
Certolizumab Pegol
golimumab
Drug-Related side effects and adverse reactions
Infection reactivation
Reinfection tuberculosis (disorder)
Reactivation of hepatitis B viral hepatitis (disorder)
Reactivation of hepatitis C viral hepatitis (disorder)
leukoencephalopathy, progressive multifocal
lymphoproliferative disorders
cardiovascular diseases
Liver function tests outside reference range (finding)
hypercholesterolemia
leukopenia
hypogammaglobulinemia
antibodies, antinuclear
Injection related reaction
Injection site reaction
drug eruptions
Drug-induced pneumonitis (disorder)
tumor necrosis factors
opportunistic infections
agammaglobulinemia
antibodies, monoclonal
Tumor Necrosis Factor Inhibitors
---
https://www.has-sante.fr/portail/jcms/c_2813812/fr/cimzia
2017
false
false
false
France
French
evaluation of the transparency committee
cimzia
Certolizumab Pegol
---
https://www.has-sante.fr/portail/jcms/c_2800419/fr/cimzia
2017
false
false
false
France
French
evaluation of the transparency committee
cimzia
Certolizumab Pegol
---
http://www.has-sante.fr/portail/jcms/c_2741827/fr/cimzia
2017
false
false
false
France
French
evaluation of the transparency committee
Pre-filled Pen Syringe
certolizumab pegol
cimzia
Certolizumab Pegol
---
http://www.has-sante.fr/portail/jcms/c_2583130/fr/cimzia
2016
false
France
French
evaluation of the transparency committee
injections, subcutaneous
certolizumab pegol
tumor necrosis factor-alpha
drug therapy, combination
methotrexate
adult
arthritis, psoriatic
treatment outcome
insurance, health, reimbursement
arthritis, rheumatoid
Non-radiographic axial spondyloarthritis
Axial spondyloarthritis
spondylarthritis
spondylitis, ankylosing
Certolizumab Pegol
Tumor Necrosis Factor Inhibitors
---
http://www.has-sante.fr/portail/jcms/c_2671761/fr/cimzia
2016
false
false
false
France
French
evaluation of the transparency committee
cimzia
Certolizumab Pegol
---
http://www.has-sante.fr/portail/jcms/c_2671761/fr/cimzia-certolizumab-pegol-anti-tnf
2016
false
false
false
France
French
evaluation of the transparency committee
treatment outcome
insurance, health, reimbursement
adult
arthritis, rheumatoid
drug therapy, combination
injections, subcutaneous
certolizumab pegol
methotrexate
guidelines for drug use
cimzia
Certolizumab Pegol
tumor necrosis factor-alpha
Tumor Necrosis Factor Inhibitors
---
Summary Safety Review - Tumour Necrosis Factor (TNF) alpha blockers (SIMPONI and CIMZIA)
- Assessing the Potential Risk of Liver Inflammation (Autoimmune Hepatitis)
https://www.hc-sc.gc.ca/dhp-mps/medeff/reviews-examens/tnf-fnt-2-fra.php
2016
false
false
false
Canada
French
tumor necrosis factor-alpha
drug evaluation
risk assessment
hepatitis, autoimmune
canada
Tumor necrosis factor alpha (TNF-α) inhibitors
psoriasis
arthritis, rheumatoid
crohn disease
colitis, ulcerative
golimumab
Certolizumab Pegol
antibodies, monoclonal
Tumor Necrosis Factor Inhibitors
---
http://www.has-sante.fr/portail/jcms/c_2583133/en/cimzia
http://www.has-sante.fr/portail/jcms/c_2583133/fr/cimzia-certolizumab-pegol-anti-tnf
2015
false
France
French
evaluation of the transparency committee
injections, subcutaneous
certolizumab pegol
tumor necrosis factor-alpha
drug therapy, combination
methotrexate
adult
arthritis, psoriatic
treatment outcome
insurance, health, reimbursement
Certolizumab Pegol
guidelines for drug use
Tumor Necrosis Factor Inhibitors
---
http://www.has-sante.fr/portail/jcms/c_1758668/fr/cimzia
2014
false
France
French
evaluation of the transparency committee
injections, subcutaneous
certolizumab pegol
tumor necrosis factor-alpha
adult
treatment outcome
spondylarthritis
spondylitis, ankylosing
guidelines for drug use
Certolizumab Pegol
Tumor Necrosis Factor Inhibitors
---
http://www.has-sante.fr/portail/jcms/c_1774104/fr/cimzia
http://www.has-sante.fr/portail/jcms/c_1774104/fr/cimzia-certolizumab-pegol-anti-tnf
2014
false
France
French
evaluation of the transparency committee
injections, subcutaneous
certolizumab pegol
tumor necrosis factor-alpha
drug therapy, combination
methotrexate
adult
arthritis, psoriatic
treatment outcome
insurance, health, reimbursement
guidelines for drug use
Certolizumab Pegol
Tumor Necrosis Factor Inhibitors
---
http://www.cochrane.org/fr/CD007649
2014
false
United Kingdom
France
French
Certolizumab Pegol
meta-analysis
arthritis, rheumatoid
adult
treatment outcome
french abstract
---
http://www.lecrat.eu/?s=Certolizumab
2013
false
France
French
drug information
certolizumab pegol
injections, subcutaneous
tumor necrosis factor-alpha
immunosuppressive agents
pregnancy
immunocompromised host
vaccination
infant, newborn
Certolizumab Pegol
Tumor Necrosis Factor Inhibitors
---
http://www.has-sante.fr/portail/jcms/c_1716271/fr/cimzia
http://www.has-sante.fr/portail/jcms/c_1716270/fr/cimzia18122013avisct13317
2013
false
France
French
evaluation of the transparency committee
injections, subcutaneous
certolizumab pegol
tumor necrosis factor-alpha
drug therapy, combination
methotrexate
arthritis, rheumatoid
adult
Certolizumab Pegol
Tumor Necrosis Factor Inhibitors
---
https://www.ema.europa.eu/medicines/human/EPAR/Cimzia
2012
false
United Kingdom
English
French
syndication feed
Certolizumab Pegol
Certolizumab Pegol
arthritis, rheumatoid
adult
aged
drug interactions
pregnancy
breast feeding
drug evaluation, preclinical
injections, subcutaneous
drug approval
drug labeling
treatment outcome
drug therapy, combination
immunosuppressive agents
immunosuppressive agents
tumor necrosis factor-alpha
drug evaluation
summary of product characteristics
package leaflet
Tumor Necrosis Factor Inhibitors
---
http://www.has-sante.fr/portail/jcms/c_957678/cimzia-certolizumab-pegol-anti-tnf
http://www.has-sante.fr/portail/jcms/c_938150/cimzia-ct-7358
http://www.has-sante.fr/portail/jcms/c_957675/synthese-d-avis-cimzia-ct-7358
2010
false
France
French
Certolizumab Pegol
Certolizumab Pegol
certolizumab pegol
tumor necrosis factor-alpha
drug therapy, combination
arthritis, rheumatoid
methotrexate
adult
insurance, health, reimbursement
treatment outcome
injections, subcutaneous
evaluation of the transparency committee
guidelines for drug use
Tumor Necrosis Factor Inhibitors
---
http://www.meddispar.fr/medicaments/3973200
2010
false
France
French
Certolizumab Pegol
certolizumab pegol
legislation, drug
drug prescriptions
injections
arthritis, rheumatoid
adult
drug information
---