tumor necrosis factors

Preferred Label : tumor necrosis factors;

MeSH definition : A family of proteins that were originally identified by their ability to cause NECROSIS of NEOPLASMS. Their necrotic effect on cells is mediated through TUMOR NECROSIS FACTOR RECEPTORS which induce APOPTOSIS.;

MeSH synonym : receptor ligands, tnf; necrosis factors, tumor; tnf receptor ligands;

Related MeSH term : tumor necrosis factor superfamily ligands;

Is substance : O;

Details

Origin ID

D048069;

UMLS CUI

C0041368;

Allowable qualifiers
- administration and dosage [MeSH Qualifier]
- adverse effects [MeSH Qualifier]
- agonists [MeSH Qualifier]
- analysis [MeSH Qualifier]
- antagonists and inhibitors [MeSH Qualifier]
- biosynthesis [MeSH Qualifier]
- blood [MeSH Qualifier]
- cerebrospinal fluid [MeSH Qualifier]
- chemical synthesis [MeSH Qualifier]
- chemistry [MeSH Qualifier]
- classification [MeSH Qualifier]
- contraindications [MeSH Qualifier]
- deficiency [MeSH Qualifier]
- economics [MeSH Qualifier]
- genetics [MeSH Qualifier]
- history [MeSH Qualifier]
- immunology [MeSH Qualifier]
- isolation and purification [MeSH Qualifier]
- metabolism [MeSH Qualifier]
- pharmacokinetics [MeSH Qualifier]
- pharmacology [MeSH Qualifier]
- physiology [MeSH Qualifier]
- poisoning [MeSH Qualifier]
- radiation effects [MeSH Qualifier]
- standards [MeSH Qualifier]
- supply and distribution [MeSH Qualifier]
- therapeutic use [MeSH Qualifier]
- toxicity [MeSH Qualifier]
- urine [MeSH Qualifier]
Automatic exact mappings (from CISMeF team)
- TNF Gene [NCIt concept]
- TNF Receptor Family Protein [NCIt concept]
- Tumor Necrosis Factor (CET) [NCIt concept]
- Tumor Necrosis Factor Family Gene [NCIt concept]
- tumor necrosis factor receptor binding [GO term]
Currated CISMeF NLP mapping
- Tumor Necrosis Factor Family Protein [NCIt concept]
- Tumor necrosis factor [LOINC component]
- tumor necrosis factor [Artificial nutrition thesaurus concept]
Record concept(s)
- tumor necrosis factor superfamily ligands [MeSH concept]
- tumor necrosis factors [MeSH concept]
Related MeSH Supplementary Concept(s)
- C1QTNF3 protein, human [MeSH Supplementary Concept]
- C1qTNF6 protein, human [MeSH Supplementary Concept]
- M-sec protein, mouse [MeSH Supplementary Concept]
- TNFSF12 protein, human [MeSH Supplementary Concept]
- TNFSF12 protein, zebrafish [MeSH Supplementary Concept]
- TNFSF18 protein, human [MeSH Supplementary Concept]
- Tnfsf12 protein, mouse [MeSH Supplementary Concept]
- Tnfsf12 protein, rat [MeSH Supplementary Concept]
- Tnfsf18 protein, mouse [MeSH Supplementary Concept]
- Tnfsf4 protein, mouse [MeSH Supplementary Concept]
- Tnfsf4 protein, rat [MeSH Supplementary Concept]
Related MeSH term(s)
- Tumor Necrosis Factor Inhibitors [MeSH Descriptor]
See also
- oncology [CISMeF Metaterm]
See also (suggested by CISMeF)
- receptors, tumor necrosis factor [MeSH Descriptor]
See also inter- (CISMeF)
- Recombinant Tumor Necrosis Factor Family Protein [NCIt concept]
- Substance with tumor necrosis factor alpha inhibitor mechanism of action (substance) [SNOMED CT concept]
- Tumor Necrosis Factor Measurement [NCIt concept]
- Tumor necrosis factor [OMIM gene]
- Tumor necrosis factor (substance) [SNOMED CT concept]
- tumor necrosis factor [SNOMED Notion]
- tumor necrosis factor [HGNC gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Immunologic Factor [UMLS semantic type]
UMLS correspondences (same concept)
- Tumor Necrosis Factor Family Protein [NCIt concept]
- Tumor necrosis factor [LOINC component]
Validated automatic mappings to BTNT
- Tumor Necrosis Factor [NCIt concept]
- Tumor necrosis factor.alpha [LOINC component]

Keyword's position in hierarchy(ies) :

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