interleukin 1 receptor antagonist protein

Preferred Label : interleukin 1 receptor antagonist protein;

MeSH definition : A ligand that binds to but fails to activate the INTERLEUKIN 1 RECEPTOR. It plays an inhibitory role in the regulation of INFLAMMATION and FEVER. Several isoforms of the protein exist due to multiple ALTERNATIVE SPLICING of its mRNA.;

MeSH synonym : il1 inhibitor, urine-derived; il1 febrile inhibitor; urine-derived il1 inhibitor; urine derived il1 inhibitor; febrile inhibitor, il1; interleukin 1 inhibitor, urine; il-1 inhibitor, urine; il 1 inhibitor, urine; urine il-1 inhibitor; il-1ra;

CISMeF synonym : amgen brand of anakinra; anakinra amgen brand; anakinra synergen brand; synergen brand of anakinra;

MeSH hyponym : anakinra; antril; kineret;

MeSH Related Number : anakinra; 9013DUQ28K;

Related CAS MeSH : 9013DUQ28K (Anakinra);

Wikipedia link : https://en.wikipedia.org/wiki/Anakinra;

Is substance : O;

Details

Origin ID

D053590;

UMLS CUI

C1704264;

ATC code(s)
- interleukin inhibitors [ATC Code]
ATC code(s)
- anakinra [ATC Code]
Allowable qualifiers
- administration and dosage [MeSH Qualifier]
- adverse effects [MeSH Qualifier]
- agonists [MeSH Qualifier]
- analysis [MeSH Qualifier]
- antagonists and inhibitors [MeSH Qualifier]
- biosynthesis [MeSH Qualifier]
- blood [MeSH Qualifier]
- cerebrospinal fluid [MeSH Qualifier]
- chemical synthesis [MeSH Qualifier]
- chemistry [MeSH Qualifier]
- classification [MeSH Qualifier]
- contraindications [MeSH Qualifier]
- deficiency [MeSH Qualifier]
- drug effects [MeSH Qualifier]
- economics [MeSH Qualifier]
- genetics [MeSH Qualifier]
- history [MeSH Qualifier]
- immunology [MeSH Qualifier]
- isolation and purification [MeSH Qualifier]
- metabolism [MeSH Qualifier]
- pharmacokinetics [MeSH Qualifier]
- pharmacology [MeSH Qualifier]
- physiology [MeSH Qualifier]
- poisoning [MeSH Qualifier]
- radiation effects [MeSH Qualifier]
- standards [MeSH Qualifier]
- supply and distribution [MeSH Qualifier]
- therapeutic use [MeSH Qualifier]
- toxicity [MeSH Qualifier]
- ultrastructure [MeSH Qualifier]
- urine [MeSH Qualifier]
Automatic exact mappings (from CISMeF team)
- Anakinra [LOINC component]
- Anakinra [ICD-11 Extension code]
- Anakinra [NCIt concept]
- IL1R1 wt Allele [NCIt concept]
- IL1RN Gene [NCIt concept]
- IL1RN wt Allele [NCIt concept]
- Interleukin 1 Receptor Antagonist Measurement [NCIt concept]
- Interleukin 1 receptor antagonist [OMIM gene]
- Interleukin 1 receptor, type I [OMIM gene]
- Interleukin-1 Receptor Antagonist Protein [NCIt concept]
- Product containing anakinra (medicinal product) [SNOMED CT concept]
- Product containing interleukin 1 receptor antagonist (product) [SNOMED CT concept]
- anakinra [ATC Code]
- interleukin 1 receptor antagonist [ORDO Gene]
- interleukin-1 receptor antagonist activity [GO term]
CISMeF manual mappings
- Substance with interleukin 1 receptor antagonist mechanism of action (substance) [SNOMED CT concept]
Pharmacological action(s)
- antirheumatic agents [MeSH Descriptor]
Record concept(s)
- anakinra [MeSH concept]
- antril [MeSH concept]
- interleukin 1 receptor antagonist protein [MeSH concept]
- kineret [MeSH concept]
Related MeSH Supplementary Concept(s)
- IL-1ra-Fc-IL-18bp fusion protein [MeSH Supplementary Concept]
- IL1RN protein, human [MeSH Supplementary Concept]
- Il1rn protein, mouse [MeSH Supplementary Concept]
- deficiency of interleukin-1 receptor antagonist [MeSH Supplementary Concept]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
Validated automatic mappings to BTNT
- Anakinra [International Nonproprietary Name]
- Anakinra (substance) [SNOMED CT concept]
- Recombinant Interleukin-1 Receptor Antagonist [NCIt concept]
- anakinra [COVID-19 Thesaurus concept]

Keyword's position in hierarchy(ies) :

Main resources

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