Interleukin-1 Receptor Antagonist Protein

Preferred Label : Interleukin-1 Receptor Antagonist Protein;

NCIt synonyms : IL1 Inhibitor; Intracellular IL-1 Receptor Antagonist Type II; ICIL-1RA; IL-1RN; Intracellular Interleukin-1 Receptor Antagonist; IL-1ra; IRAP; IL1RN;

NCIt definition : Interleukin-1 receptor antagonist protein (177 aa, 20 kDa) is encoded by the human IL1RN gene. This protein is involved in the inhibition of the interaction between interleukin-1 and its receptor.;

NCI Metathesaurus CUI : CL473806;

Details

Origin ID

C98166;

UMLS CUI

C1504688;

Automatic exact mappings (from CISMeF team)
- Interleukin 1 receptor antagonist [OMIM gene]
- Interleukin 1 receptor, type I [OMIM gene]
- Leucyl-cystinyl aminopeptidase [OMIM gene]
- interleukin 1 inhibitor [COVID-19 Thesaurus concept]
- interleukin 1 receptor antagonist [ORDO Gene]
- interleukin 1 receptor antagonist [HGNC gene]
- interleukin 1 receptor antagonist protein [MeSH Descriptor]
- interleukin 1 receptor antagonist protein [MeSH concept]
- interleukin-1 receptor antagonist activity [GO term]
OMIM relation
- Interleukin 1 receptor antagonist [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Biologically Active Substance [UMLS semantic type]
UMLS correspondences (same concept)
- IL1RN protein, human [MeSH concept]
- IL1RN protein, human [MeSH Supplementary Concept]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
endogenous_product_related_to
- Anakinra [NCIt concept]
gene_encodes_gene_product
- Cytokine Gene [NCIt concept]
- IL1RN Gene [NCIt concept]
- Interleukin Gene [NCIt concept]
gene_product_has_associated_anatomy
- Cytoplasm [NCIt concept]
- Extracellular Space [NCIt concept]
gene_product_is_element_in_pathway
- IL1-Mediated Signaling Pathway [NCIt concept]
- IL1R Signaling Pathway [NCIt concept]
gene_product_plays_role_in_biological_process
- Cell Proliferation Regulatory Process [NCIt concept]
- Cytokine Receptor Binding [NCIt concept]
- Cytokine Signaling [NCIt concept]
- Cytokine Signaling Process [NCIt concept]
- Inflammatory Response [NCIt concept]
- Intercellular Communication Process [NCIt concept]
- Interleukin Signaling Process [NCIt concept]
- Negative Regulation of Interleukin Signaling [NCIt concept]

Keyword's position in hierarchy(ies) :

You can consult :

recommendations
documents concerning education
documents for patients