Anakinra - CISMeF

Preferred Label : Anakinra;

NCIt synonyms : rIL-1ra; rIL1RN;

NCIt related terms : Kinaret;

NCIt definition : A recombinant human nonglycosylated interleukin-1 (IL-1) receptor antagonist with potential antineoplastic activity. Anakinra binds to the IL-1 receptor, thereby blocking the binding of the IL-1 to and activation of its receptor. Blockade of IL-1 activity may inhibit the cascade of downstream pro-angiogenic factors such as vascular endothelial cell growth factor, tumor necrosis factor-alpha, and IL-6, resulting in inhibition of tumor angiogenesis. (NCI04);

Alternative definition : NCI-GLOSS: A substance that is used to treat rheumatoid arthritis, and is being studied in the treatment of cancer. Anakinra blocks the action of interleukin 1 (IL-1). It is a type of interleukin receptor antagonist.;

UNII : 9013DUQ28K;

CAS number : 143090-92-0;

Drug name : Kineret;

Codes from synonyms : CDR0000347382; CDR0000346487; 12282;

Details

Origin ID

C38717;

UMLS CUI

C0245109;

See also inter- (CISMeF)
- Product containing anakinra (medicinal product) [SNOMED CT concept]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
UMLS correspondences (same concept)
- Anakinra [International Nonproprietary Name]
- Anakinra [LOINC component]
- Anakinra (substance) [SNOMED CT concept]
- Product containing anakinra (medicinal product) [SNOMED CT concept]
- anakinra [ATC Code]
- anakinra [MeSH concept]
concept_is_in_subset
- CTRP Agent Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
- FDA Established Names and Unique Ingredient Identifier Codes Terminology [NCIt concept]
- GDC Terminology [NCIt concept]
- GDC Therapeutic Agent Terminology [NCIt concept]
- GDC Value Terminology [NCIt concept]
- HemOnc Agent Terminology [NCIt concept]
- NCI Drug Dictionary Terminology [NCIt concept]
- NCIt Antineoplastic Agent Terminology [NCIt concept]
- NCIt COVID-19 Agent Terminology [NCIt concept]
- NCIt COVID-19 Terminology [NCIt concept]
has_target
- Interleukin-1 Receptor Type 1 [NCIt concept]
is_component_of_chemotherapy_regimen
- Anakinra Regimen [NCIt concept]
is_related_to_endogenous_product
- Interleukin-1 Receptor Antagonist Protein [NCIt concept]

Keyword's position in hierarchy(ies) :

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