Negative Regulation of Interleukin Signaling

Preferred Label : Negative Regulation of Interleukin Signaling;

NCIt synonyms : Interleukin Suppression;

NCIt definition : Any physiologic process which occurs in response to ligation of an interleukin receptor with a cognate ligand, and results in a reduced number of active signaling molecules within the target cell. This process is involved in regulating the extent of the extent of the response to receptor binding, and in regulating active populations of T, B and hemopoietic cells.;

Details

Origin ID

C40599;

UMLS CUI

C1512854;

Semantic type(s)
- Physiologic Function [UMLS semantic type]
biological_process_involves_gene_product
- Interleukin-1 Receptor Antagonist Protein [NCIt concept]
- Interleukin-1 Receptor Type 2 [NCIt concept]
- Interleukin-18-Binding Protein [NCIt concept]
- Interleukin-36 Receptor Antagonist Protein [NCIt concept]
process_involves_gene
- IL18BP Gene [NCIt concept]
- IL18BP wt Allele [NCIt concept]
- IL1R2 Gene [NCIt concept]
- IL1R2 wt Allele [NCIt concept]
- IL1RN Gene [NCIt concept]
- IL1RN wt Allele [NCIt concept]
- IL36RN Gene [NCIt concept]
- IL36RN wt Allele [NCIt concept]

Keyword's position in hierarchy(ies) :

You can consult :

recommendations
documents concerning education
documents for patients