IL36RN wt Allele

Preferred Label : IL36RN wt Allele;

NCIt synonyms : FIL1-DELTA; IL36RA; Interleukin 36 Receptor Antagonist wt Allele; IL-1 Related Protein Gene; MGC29840; Interleukin 1 Receptor Antagonist Homolog 1 Gene; IL1RP3; IL-1F5 (IL-1HY1, FIL1-Delta, IL-1RP3, IL-1L1, IL-1-Delta) Gene; Interleukin 1 Family, Member 5 Gene; PSORS14; FIL1(DELTA); IL1HY1; IL1L1; IL1F5 (Canonical Product IL-1F5a) Gene; Family of Interleukin 1-Delta Gene; Interleukin 1 Family, Member 5 (Delta) Gene; IL-36Ra; FIL1D; IL1F5; FIL1; PSORP;

NCIt definition : Human IL36RN wild-type allele is located in the vicinity of 2q14.1 and is approximately 7 kb in length. This allele, which encodes interleukin-36 receptor antagonist protein, is involved in binding to interleukin-1 receptor-like 2, which inhibits interleukin-36 binding and signaling. Mutations in the gene are associated with pustular psoriasis 14 (deficiency of IL36RN).;

NCI Metathesaurus CUI : CL1920676;

GenBank Accession Number : AF201830;

Details

Origin ID

C201798;

UMLS CUI

C5891038;

OMIM relation
- Interleukin 36 receptor antagonist [OMIM gene]
Semantic type(s)
- Gene or Genome [UMLS semantic type]
gene_found_in_organism
- Human [NCIt concept]
gene_in_chromosomal_location
- 2q14.1 [NCIt concept]
gene_is_element_in_pathway
- Cytokine-Cytokine Receptor Signaling Pathway [NCIt concept]
gene_plays_role_in_process
- Antimicrobial Effect [NCIt concept]
- Cell Proliferation Regulatory Process [NCIt concept]
- Cytokine Receptor Binding [NCIt concept]
- Cytokine Signaling [NCIt concept]
- Cytokine Signaling Process [NCIt concept]
- Intercellular Communication Process [NCIt concept]
- Interleukin Signaling Process [NCIt concept]
- Negative Regulation of Interleukin Signaling [NCIt concept]

Keyword's position in hierarchy(ies) :

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