IL1R1 wt Allele

Preferred Label : IL1R1 wt Allele;

NCIt synonyms : IL1RA; IL1R; Interleukin 1 Receptor, Type I wt Allele; CD121A; Interleukin 1 Receptor Gene; D2S1473; Interleukin 1 Receptor, Alpha, Type I Gene; IL-1R-alpha; P80;

NCIt definition : Human IL1R1 wild-type allele is located within 2q12 and is approximately 26 kb in length. This allele, which encodes interleukin-1 receptor type 1 protein, plays a role in the mediation of many cytokine induced immune and inflammatory responses.;

GenBank Accession Number : NM_000877;

Details

Origin ID

C51360;

UMLS CUI

C1708432;

Automatic exact mappings (from CISMeF team)
- Interleukin 1 receptor antagonist [OMIM gene]
- Interleukin 1 receptor, type I [OMIM gene]
- WD repeat domain 48 [ORDO Gene]
- Wd repeat-containing protein 48 [OMIM gene]
- interleukin 1 receptor antagonist [ORDO Gene]
- interleukin 1 receptor antagonist protein [MeSH Descriptor]
- interleukin-1 receptor activity [GO term]
- interleukin-1 receptor antagonist activity [GO term]
- receptors, interleukin-1 [MeSH Descriptor]
- receptors, interleukin-1 type i [MeSH Descriptor]
OMIM relation
- Interleukin 1 receptor, type I [OMIM gene]
Semantic type(s)
- Gene or Genome [UMLS semantic type]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_found_in_organism
- Human [NCIt concept]
gene_has_physical_location
- 2: 102228920-102254852 [NCIt concept]
gene_in_chromosomal_location
- 2q12 [NCIt concept]
gene_is_element_in_pathway
- Amoebiasis Pathway [NCIt concept]
- Apoptosis Pathway [NCIt concept]
- Cytokine-Cytokine Receptor Signaling Pathway [NCIt concept]
- Hematopoietic Cell Lineage Pathway [NCIt concept]
- IL1-Mediated Signaling Pathway [NCIt concept]
- IL12-Mediated Signaling Pathway [NCIt concept]
- IL1R Signaling Pathway [NCIt concept]
- MAPK Signaling Pathway [NCIt concept]
- NFKB Signaling Pathway [NCIt concept]
gene_plays_role_in_process
- Cytokine Signaling [NCIt concept]
- Cytokine Signaling Process [NCIt concept]
- Intercellular Communication Process [NCIt concept]
- Interleukin Signaling Process [NCIt concept]
- Ligand Binding [NCIt concept]
- Receptor Signaling [NCIt concept]

Keyword's position in hierarchy(ies) :

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