Hepatocyte Nuclear Factor 1-Alpha

Preferred Label : Hepatocyte Nuclear Factor 1-Alpha;

NCIt synonyms : TCF-1; HNF-1-Alpha; HNF1A; TCF1; LFB1; Liver-Specific Transcription Factor LF-B1; HNF-1A; Transcription Factor 1;

NCIt definition : Hepatocyte nuclear factor 1-alpha (631 aa, 67 kDa) is encoded by the human HNF1A gene. This protein plays a role in transcriptional regulation.;

NCIt note : Hepatocyte nuclear factor 1-alpha binds to the inverted palindrome 5'-GTTAATNATTAAC-3'. (UniProt);

Details

Origin ID

C97827;

UMLS CUI

C1451774;

Automatic exact mappings (from CISMeF team)
- HNF1 homeobox A [ORDO Gene]
- Hnf1 homeobox a [OMIM gene]
- Transcription factor 7 [OMIM gene]
- hepatocyte nuclear factor 1-alpha [MeSH Descriptor]
- hepatocyte nuclear factor 1-alpha [MeSH concept]
OMIM relation
- Hnf1 homeobox a [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Biologically Active Substance [UMLS semantic type]
UMLS correspondences (same concept)
- HNF1A protein, human [MeSH concept]
- HNF1A protein, human [MeSH Supplementary Concept]
- hepatocyte nuclear factor 1-alpha [MeSH concept]
- hepatocyte nuclear factor 1-alpha [MeSH Descriptor]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_encodes_gene_product
- HNF1A Gene [NCIt concept]
- Regulatory Gene [NCIt concept]
- Transcription Factor Gene [NCIt concept]
- Transcription Regulation Gene [NCIt concept]
gene_product_expressed_in_tissue
- Liver [NCIt concept]
gene_product_has_associated_anatomy
- Nucleus [NCIt concept]
gene_product_has_biochemical_function
- DNA Binding Protein [NCIt concept]
- Homeobox Family Protein [NCIt concept]
gene_product_has_structural_domain_or_motif
- Homeo Domain [NCIt concept]
gene_product_is_element_in_pathway
- ALK Pathway [NCIt concept]
- FOXA2 and FOXA3 Transcription Factor Signaling Pathway [NCIt concept]
- Growth Hormone Signaling Pathway [NCIt concept]
- Maturity Onset Diabetes of the Young Pathway [NCIt concept]
- Notch and Wnt Signaling Pathway [NCIt concept]
- Presenilin Action in Notch and Wnt Signaling Pathways [NCIt concept]
- SRF Activation Pathway [NCIt concept]
- Segmentation Clock Pathway [NCIt concept]
- WNT Signaling Pathway BioCarta [NCIt concept]
gene_product_plays_role_in_biological_process
- DNA Binding [NCIt concept]
- Glucose Transport Induction [NCIt concept]
- Transcriptional Activation [NCIt concept]
- Transcriptional Regulation [NCIt concept]

Keyword's position in hierarchy(ies) :

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