POU Domain - CISMeF

Preferred Label : POU Domain;

NCIt definition : The POU domain is a bipartite DNA binding domain recognized originally as a shared structural motif in the Pit-1, Oct-1/Oct-2, and Unc-86 transcription factors (POU). It is comprised by a C-terminal homeo domain, and an N-terminal POU-specific domain, separated by a non-conserved linker. The POU-specific domain, like the homeo domain, is folded in a helix-turn-helix motif.;

Details

Origin ID

C13423;

UMLS CUI

C1518803;

Semantic type(s)
- Amino Acid Sequence [UMLS semantic type]
is_structural_domain_or_motif_of_gene_product
- POU Domain, Class 2, Transcription Factor 1 [NCIt concept]
- POU Domain, Class 2, Transcription Factor 2 [NCIt concept]
- POU Domain, Class 2, Transcription Factor 3 [NCIt concept]
- POU Domain, Class 3, Transcription Factor 2 [NCIt concept]
- POU Domain, Class 5, Transcription Factor 1 [NCIt concept]
- Pituitary-Specific Positive Transcription Factor 1 [NCIt concept]
- Putative POU Domain, Class 5, Transcription Factor 1B [NCIt concept]

Keyword's position in hierarchy(ies) :

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