POU Domain, Class 2, Transcription Factor 3

Preferred Label : POU Domain, Class 2, Transcription Factor 3;

NCIt synonyms : OTF-11; Octamer-Binding Protein 11; OCT-11; POU Class 2 Homeobox 3; Octamer-Binding Transcription Factor 11; Transcription Factor Skn-1; Transcription Factor PLA-1; POU2F3;

NCIt definition : POU domain, class 2, transcription factor 3 (436 aa, 47 kDa) is encoded by the human POU2F3 gene. This protein is involved in cellular proliferation and differentiation.;

NCIt note : POU domain, class 2, transcription factor 3 binds to the octamer motif (5'-ATTTGCAT-3'). (UniProt);

Détails

Origin ID

C185592;

UMLS CUI

C1434458;

OMIM relation
- Pou domain, class 2, transcription factor 3 [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Biologically Active Substance [UMLS semantic type]
UMLS correspondences (same concept)
- POU2F3 protein, human [MeSH Supplementary Concept]
- POU2F3 protein, human [MeSH concept]
gene_encodes_gene_product
- POU2F3 Gene [NCIt concept]
- Regulatory Gene [NCIt concept]
- Transcription Factor Gene [NCIt concept]
- Transcription Regulation Gene [NCIt concept]
gene_product_expressed_in_tissue
- Epidermis [NCIt concept]
gene_product_has_associated_anatomy
- Keratinocyte [NCIt concept]
- Nucleus [NCIt concept]
gene_product_has_biochemical_function
- DNA Binding Protein [NCIt concept]
- Sequence-Specific DNA Binding Protein [NCIt concept]
gene_product_has_chemical_classification
- Homeobox Family Protein [NCIt concept]
gene_product_has_structural_domain_or_motif
- Homeo Domain [NCIt concept]
- POU Domain [NCIt concept]
gene_product_plays_role_in_biological_process
- DNA Binding [NCIt concept]
- Keratinocyte Differentiation [NCIt concept]
- Stimulation of Cell Proliferation [NCIt concept]
- Transcriptional Activation [NCIt concept]
- Transcriptional Regulation [NCIt concept]

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