POU Domain, Class 2, Transcription Factor 2

Preferred Label : POU Domain, Class 2, Transcription Factor 2;

NCIt synonyms : OCT-2; Lymphoid-Specific OTF2; POU Homeodomain Transcription Factor 2; Lymphoid-Restricted Immunoglobulin Octamer Binding Protein NF-A2; Octamer Transcription Factor-2; Octamer-Binding Transcription Factor 2; OTF-2; POU2F2; Octamer Binding Protein 2;

NCIt definition : POU domain, class 2, transcription factor 2 (479 aa, 51 kDa) is encoded by the human POU2F2 gene. This protein is involved in both immune responses and transcriptional regulation.;

NCIt note : POU domain, class 2, transcription factor 2 binds to the octamer motif (5'-ATTTGCAT-3'). (UniProt);

Details

Origin ID

C17539;

UMLS CUI

C1442823;

Currated CISMeF NLP mapping
- octamer transcription Factor-2 [MeSH concept]
- octamer transcription factor-2 [MeSH Descriptor]
OMIM relation
- Pou domain, class 2, transcription factor 2 [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Biologically Active Substance [UMLS semantic type]
UMLS correspondences (same concept)
- POU2F2 protein, human [MeSH concept]
- POU2F2 protein, human [MeSH Supplementary Concept]
gene_encodes_gene_product
- POU2F2 Gene [NCIt concept]
- Regulatory Gene [NCIt concept]
- Transcription Factor Gene [NCIt concept]
- Transcription Regulation Gene [NCIt concept]
gene_product_expressed_in_tissue
- B-Lymphocyte [NCIt concept]
gene_product_has_associated_anatomy
- Nucleus [NCIt concept]
gene_product_has_biochemical_function
- DNA Binding Protein [NCIt concept]
- Sequence-Specific DNA Binding Protein [NCIt concept]
gene_product_has_chemical_classification
- Homeobox Family Protein [NCIt concept]
gene_product_has_organism_source
- Human [NCIt concept]
gene_product_has_structural_domain_or_motif
- Homeo Domain [NCIt concept]
- POU Domain [NCIt concept]
gene_product_is_element_in_pathway
- BCR Immune Response Signaling Pathway [NCIt concept]
gene_product_plays_role_in_biological_process
- DNA Binding [NCIt concept]
- Transcriptional Activation [NCIt concept]
- Transcriptional Regulation [NCIt concept]

Keyword's position in hierarchy(ies) :

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