Preferred Label : POU Domain, Class 3, Transcription Factor 2;
NCIt synonyms : Octamer-Binding Protein 7; Nervous System-Specific Octamer-Binding Transcription Factor N-Oct-3; Oct-7; OTF-7; Brain-2; Brain-Specific Homeobox/POU Domain Protein 2; Brn-2; Octamer-Binding Transcription Factor 7;
NCIt definition : POU domain, class 3, transcription factor 2 (443 aa, 47 kDa) is encoded by the human
POU3F2 gene. This protein is involved in the modulation of both cell proliferation
and transcription.;
NCIt note : POU domain, class 3, transcription factor 2 binds preferentially to the recognition
sequence which consists of two distinct half-sites, ('GCAT') and ('TAAT'), separated
by a nonconserved spacer region of 0, 2, or 3 nucleotides. This protein positively
regulates expression of the genes under the control of both the corticotropin-releasing
hormone (CRH) and CRH II promoters. (UniProt);
Origin ID : C98199;
UMLS CUI : C1310510;
OMIM relation
- Semantic type(s)
- UMLS correspondences (same concept)
- gene_encodes_gene_product
- gene_product_has_associated_anatomy
- gene_product_has_biochemical_function
- gene_product_has_chemical_classification
- gene_product_has_structural_domain_or_motif
- gene_product_plays_role_in_biological_process
