CCND3 wt Allele

Preferred Label : CCND3 wt Allele;

NCIt synonyms : RP5-973N23.3; Cyclin D3 wt Allele; D3-Type Cyclin Gene;

NCIt definition : Human CCND3 wild-type allele is located in the vicinity of 6p21 and is approximately 115 kb in length. This allele, which encodes G1/S-specific cyclin-D3 protein, plays a role in the modulation of cell cycle progression. A translocation of this gene and the IGH gene locus may be associated with splenic marginal zone B-cell lymphoma.;

GenBank Accession Number : NM_001136017;

Details

Origin ID

C97382;

UMLS CUI

C3273386;

Automatic exact mappings (from CISMeF team)
- cyclin D3 [MeSH Descriptor]
OMIM relation
- Cyclin d3 [OMIM gene]
Semantic type(s)
- Gene or Genome [UMLS semantic type]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_found_in_organism
- Human [NCIt concept]
gene_in_chromosomal_location
- 6p21 [NCIt concept]
gene_involved_in_pathogenesis_of_disease
- Mantle Cell Lymphoma with CCND3 Rearrangement [NCIt concept]
gene_is_element_in_pathway
- Cell Cycle Pathway [NCIt concept]
- Coregulation Pathway for Androgen Receptor Activity [NCIt concept]
- Cyclin Regulation of Cell Cycle Pathway [NCIt concept]
- E2F Transcription Factor Pathway [NCIt concept]
- Focal Adhesion Pathway [NCIt concept]
- IL2/STAT5 Signaling Pathway [NCIt concept]
- Jak-STAT Signaling Pathway [NCIt concept]
- Wnt Signaling Pathway KEGG [NCIt concept]
- p53 Signaling Pathway KEGG [NCIt concept]
gene_plays_role_in_process
- Cell Cycle Process [NCIt concept]
- Cell Cycle Progression [NCIt concept]
- Cell Cycle Regulation Process [NCIt concept]
- Protein Phosphorylation Process [NCIt concept]

Keyword's position in hierarchy(ies) :

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