TRAF3 wt Allele

Preferred Label : TRAF3 wt Allele;

NCIt synonyms : CD40 Receptor Associated Factor 1 Gene; CRAF1; CAP-1; LAP1; CD40 Associated Protein 1 Gene; TNF Receptor-Associated Factor 3 wt Allele; IIAE5; CD40 Binding Protein Gene; CAP1; CD40BP; RNF118; TNF Receptor Associated Factor 3 Gene; TRAFAMN;

NCIt definition : Human TRAF3 wild-type allele is located in the vicinity of 14q32.32 and is approximately 127 kb in length. This allele, which encodes TNF receptor-associated factor 3 protein, plays a role in the modulation of both apoptosis and signaling pathways.;

NCIt note : Mutations in the protein-coding region of the TRAF3 gene were found in multiple myeloma. (Nature. 2011; 471: 467-472.);

GenBank Accession Number : U21092;

Details

Origin ID

C96378;

UMLS CUI

C3272747;

OMIM relation
- Tnf receptor-associated factor 3 [OMIM gene]
Semantic type(s)
- Gene or Genome [UMLS semantic type]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_found_in_organism
- Human [NCIt concept]
gene_is_element_in_pathway
- B-Cell Immune Response Pathway [NCIt concept]
- CD40/CD40L Signaling Pathway [NCIt concept]
- CD40L Signaling Pathway [NCIt concept]
- RIG-I-Like Receptor Signaling Pathway [NCIt concept]
- Small Cell Lung Cancer Pathway [NCIt concept]
- TNFR2 Signaling Pathway [NCIt concept]
- Toll-Like Receptor Signaling Pathway [NCIt concept]
gene_plays_role_in_process
- Positive Regulation of Apoptosis [NCIt concept]
- Signal Transduction [NCIt concept]
- Ubiquitinated Protein Degradation [NCIt concept]
- Ubiquitination [NCIt concept]

Keyword's position in hierarchy(ies) :

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