Nonhomologous End-Joining Factor 1

Preferred Label : Nonhomologous End-Joining Factor 1;

NCIt synonyms : XRCC4-Like Factor; Protein Cernunnos; Protein XLF; NHEJ1;

NCIt definition : Non-homologous end-joining factor 1 (299 aa, 33 kDa) is encoded by the human NHEJ1 gene. This protein is involved in both the repair of double-strand breaks in DNA and nonhomologous end-joining.;

Details

Origin ID

C88515;

UMLS CUI

C1702213;

OMIM relation
- Nonhomologous end-joining factor 1 [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Biologically Active Substance [UMLS semantic type]
UMLS correspondences (same concept)
- NHEJ1 protein, human [MeSH Supplementary Concept]
- NHEJ1 protein, human [MeSH concept]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_encodes_gene_product
- DNA Repair Gene [NCIt concept]
- NHEJ1 Gene [NCIt concept]
gene_product_is_element_in_pathway
- Non-Homologous End-Joining Pathway [NCIt concept]
gene_product_malfunction_associated_with_disease
- Severe Combined Immunodeficiency with Absence of T and B Cells [NCIt concept]
gene_product_plays_role_in_biological_process
- B-Cell Differentiation [NCIt concept]
- DNA Repair [NCIt concept]
- Nonhomologous DNA End Joining [NCIt concept]
- T-Cell Differentiation [NCIt concept]
- V(D)J Recombination [NCIt concept]

Keyword's position in hierarchy(ies) :

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