Theophylline - CISMeF

Preferred Label : Theophylline;

NCIt synonyms : 1,3-Dimethylxanthine Monohydrate; 3,7-Dihydro-1,3-dimethyl-1H-purine-2,6-dione; 3,7-Dihydro-1,3-dimethyl-1H-purine-2,6-dione Monohydrate; Theophylline Monohydrate;

NCIt related terms : Elixophyllin; Respbid;

NCIt definition : A natural alkaloid derivative of xanthine isolated from the plants Camellia sinensis and Coffea arabica. Theophylline appears to inhibit phosphodiesterase and prostaglandin production, regulate calcium flux and intracellular calcium distribution, and antagonize adenosine. Physiologically, this agent relaxes bronchial smooth muscle, produces vasodilation (except in cerebral vessels), stimulates the CNS, stimulates cardiac muscle, induces diuresis, and increases gastric acid secretion; it may also suppress inflammation and improve contractility of the diaphragm. (NCI04);

Alternative definition : NCI-GLOSS: A drug used to improve breathing in people who are short of breath. It belongs to the family of drugs called bronchodilators or respiratory smooth muscle relaxants.;

UNII : C137DTR5RG;

InChIKey : INQSMEFCAIHTJG-UHFFFAOYSA-N;

CAS number : 5967-84-0; a href https://gsrs.ncats.nih.gov/ginas/app/beta/browse-substance?search 5967-84-0 alt lien vers site G-SRS target _blank img src /img/logos/logo_g-srs.png alt Logo G-SRS /a ;

Drug name : Uniphyl; Theobid Duracap; Theochron; Slo-Phyllin; Elixophyllin; Somophyllin-CRT; Somophyllin-T; Theo-24; Slo-bid; T-Phyl; LaBID; Constant-T; Respbid;

Chemical formula : C7H8N4O2.H2O;

NSC code : 2066;

Codes from synonyms : NSC0002066; CDR0000045358; 00815;

Details

Origin ID

C872;

UMLS CUI

C0039771;

See also inter- (CISMeF)
- Product containing theophylline (medicinal product) [SNOMED CT concept]
Semantic type(s)
- Organic Chemical [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
UMLS correspondences (same concept)
- Product containing theophylline (medicinal product) [SNOMED CT concept]
- Theophylline [ICD-11 Extension code]
- Theophylline [LOINC component]
- Theophylline (substance) [SNOMED CT concept]
- theophylline [ATC Code]
- theophylline [Substance BNPC]
- theophylline [MeSH Descriptor]
- theophylline [SNOMED Notion]
- theophylline [MeSH concept]
Validated automatic mappings to BTNT
- Theophylline monohydrate (substance) [SNOMED CT concept]
- theophylline [ATC Code]
chemical_or_drug_is_metabolized_by_enzyme
- Cytochrome P450 1A2 [NCIt concept]
- Cytochrome P450 2E1 [NCIt concept]
concept_is_in_subset
- CTRP Agent Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
- FDA Established Names and Unique Ingredient Identifier Codes Terminology [NCIt concept]
- NCI Drug Dictionary Terminology [NCIt concept]
has_salt_form
- Theophylline Sodium Acetate [NCIt concept]
is_free_acid_or_base_form_of
- Theophylline Sodium Acetate [NCIt concept]

Keyword's position in hierarchy(ies) :

Main resources

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