Preferred Label : Dexmedetomidine;
NCIt synonyms : ( )-4-((S)-alpha,2,3-Trimethylbenzyl)imidazole;
NCIt definition : An imidazole derivate and active d-isomer of medetomidine with analgesic, anxiolytic
and sedative properties. Dexmedetomidine selectively binds to presynaptic alpha-2
adrenoceptors located in the brain, thereby inhibiting the release of norepinephrine
from synaptic vesicles. This leads to an inhibition of postsynaptic activation of
adrenoceptors, which inhibit sympathetic activity, thereby leading to sedation and
anxiolysis. The analgesic effect of this agent is mediated by binding to alpha-2 adrenoceptors
in the spinal cord.;
UNII : 67VB76HONO;
InChIKey : CUHVIMMYOGQXCV-NSHDSACASA-N;
CAS number : 113775-47-6; a href https://gsrs.ncats.nih.gov/ginas/app/beta/browse-substance?search 113775-47-6
alt lien vers site G-SRS target _blank img src /img/logos/logo_g-srs.png alt Logo
G-SRS /a ;
Chemical formula : C13H16N2;
ChEBI ID : CHEBI:4466;
Origin ID : C47479;
UMLS CUI : C0113293;
Semantic type(s)
- UMLS correspondences (same concept)
- Validated automatic mappings to BTNT
- concept_is_in_subset
- has_salt_form
- is_free_acid_or_base_form_of
https://pgtmsite.files.wordpress.com/2024/01/protocole_ad_dexmedetomidine_201205.pdf
2012
Canada
drug information
critical care
Dexmedetomidine
Intensive Care Stay Required
dexmedetomidine
intensive care
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https://pgtmsite.files.wordpress.com/2024/01/dexmedetomidine_intubation_es_20111228.pdf
2011
Canada
drug information
Have Thrush
endoscopes
intubation, nos
adult
Fiber Optic Device
Dexmedetomidine
Dexmedetomidine Hydrochloride
wakefulness
endoscopy
intubation
Legal Adult
Intubation Procedure
dexmedetomidine
adulthood
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https://pgtmsite.files.wordpress.com/2024/01/dexmedetomidine_sedation_consciente_es_20111207.pdf
2011
Canada
drug information
Under No Sedation
adulthood
Conscious State
anesthetics, local
Regional Anesthesia Procedure
consciousness, nos
regional anesthesia, nos
Sedated
local anesthesia, nos
anesthesia, local
Sedation
Consciousness
Awareness
Legal Adult
conscious sedation
dexmedetomidine
Am Self-Conscious
sedation, nos
sedated state
Dexmedetomidine Hydrochloride
local anesthetic, nos
adult
Dexmedetomidine
Redundancy
Local Anesthesia Procedure
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