Preferred Label : anesthetics, local;
MeSH definition : Drugs that block nerve conduction when applied locally to nerve tissue in appropriate
concentrations. They act on any part of the nervous system and on every type of nerve
fiber. In contact with a nerve trunk, these anesthetics can cause both sensory and
motor paralysis in the innervated area. Their action is completely reversible. (From
Gilman AG, et. al., Goodman and Gilman's The Pharmacological Basis of Therapeutics,
8th ed) Nearly all local anesthetics act by reducing the tendency of voltage-dependent
sodium channels to activate.;
MeSH synonym : local anesthetics; anesthetics, conduction-blocking; conduction blocking anesthetics; anesthetics, conduction blocking; conduction-blocking anesthetics; Local Anesthetic; Anesthetic, Local;
MeSH hyponym : anesthetics, topical; Topical Anesthetics;
MeSH annotation : see note at ANESTHETICS;
Wikipedia link : https://en.wikipedia.org/wiki/Local anesthetic;
Is substance : O;
action pharmacologique : O;
Origin ID : D000779;
UMLS CUI : C0002934;
ATC code(s)
- ATC code(s)
- Allowable qualifiers
- Automatic exact mappings (from CISMeF team)
- CISMeF manual mappings
- Currated CISMeF NLP mapping
- Indexing information
- Record concept(s)
- SNOMED CT : is a
- See also
- See also (suggested by CISMeF)
- See also inter- (CISMeF)
- Semantic type(s)
- Substance(s)
- QX-314 [MeSH Supplementary Concept]
- UMLS correspondences (same concept)
- Validated automatic mappings to BTNT
Drugs that block nerve conduction when applied locally to nerve tissue in appropriate
concentrations. They act on any part of the nervous system and on every type of nerve
fiber. In contact with a nerve trunk, these anesthetics can cause both sensory and
motor paralysis in the innervated area. Their action is completely reversible. (From
Gilman AG, et. al., Goodman and Gilman's The Pharmacological Basis of Therapeutics,
8th ed) Nearly all local anesthetics act by reducing the tendency of voltage-dependent
sodium channels to activate.
https://www.cochrane.org/fr/CD006712/FERTILREG_les-anesthesiques-locaux-sont-ils-efficaces-pour-le-traitement-de-la-douleur-lors-dune-interruption
2024
United Kingdom
review of literature
french abstract
Voluntary Report
What Month is it
pain management
withholding treatment
abortion, legal
pregnancy trimester, first
administration, topical
First Trimester
anesthetics, local
Tiaprofenic Acid
first trimester pregnancy
local anesthesia, nos
Treatment Interruption
local anesthetic, nos
Discontinue
Local Anesthesia Procedure
Pain Therapy
pain
abortion on demand
elective abortion
---
https://www.has-sante.fr/jcms/p_3460815/fr/antasol-180-protoxyde-d-azote/oxygene-anesthesiques-locaux
2023
false
false
false
France
evaluation of the transparency committee
Local Anesthesia Procedure
local anesthesia, nos
local anesthetic, nos
anesthetics, local
---
https://www.has-sante.fr/jcms/p_3459831/fr/emlapatch-lidocaine/-prilocaine-anesthesiques-locaux
2023
false
false
false
France
lidocaine
evaluation of the transparency committee
prilocaine
local anesthetic, nos
prilocaine
anesthetics, local
Anesthesia
local anesthesia, nos
---
https://www.cochrane.org/fr/CD000126/STROKE_lanesthesie-loco-regionale-ou-generale-est-elle-preferable-lors-dune-operation-visant-elargir-le
2021
false
true
false
United Kingdom
France
anesthetics, general
comparative study
stroke
meta-analysis
french abstract
endarterectomy, carotid
anesthesia, general
anesthetics, local
anesthesia, local
---
https://www.cochrane.org/fr/CD007337/LIVER_administration-dun-anesthesique-local-par-voie-intraperitoneale-chez-les-personnes-subissant-une
2021
false
false
false
France
United Kingdom
review of literature
french abstract
anesthetics, local
pain
treatment outcome
injections, intraperitoneal
cholecystectomy, laparoscopic
pain management
---
https://www.cochrane.org/fr/CD012310/SYMPT_administration-continue-dun-anesthesique-local-autour-de-la-plaie-pour-traiter-la-douleur-apres-une
2020
France
United Kingdom
review of literature
french abstract
Wound
incisor
persistent
Local administration
administration, topical
anesthesia, local
general surgery
pain management
abdominal pain
anesthetics, local
local anesthetic, nos
Abdomen
intestines
local government
topical route
pain
Surgery
incision of intestine, nos
Anesthesia
abdomen
operative procedure, nos
wound, nos
anesthesia, local
pain
abdomen
---
https://www.has-sante.fr/jcms/p_3067179/fr/bupivacaine-accord
2019
false
true
false
false
France
bupivacaine
adolescent
adult
anesthetics, local
pain management
acute pain
infant
child
child, preschool
evaluation of the transparency committee
bupivacaine
---
https://www.cochrane.org/fr/CD005364/lanesthesie-locale-medicament-anesthesiant-qui-est-directement-appliquee-sur-la-peau-peut-fournir-un
2019
false
false
false
France
United Kingdom
suture techniques
skin
treatment outcome
review of literature
french abstract
pain management
lacerations
anesthetics, local
administration, cutaneous
---
https://minerva-ebp.be/FR/Article/2155
2018
false
false
false
false
Belgium
French
critical appraisal or critical reading
injections, epidural
adrenal cortex hormones
anesthetics, local
time
treatment outcome
lumbar vertebrae
pain
drug therapy, combination
adult
spinal stenosis
---
http://www.cochrane.org/fr/CD010331/lanesthesie-topique-contre-la-douleur-liee-aux-piqures-chez-les-nouveau-nes
2017
false
false
false
France
United Kingdom
French
french abstract
review of literature
infant, newborn
pain
punctures
anesthetics, local
treatment outcome
---
http://www.centreantipoisons.be/professionnels-de-la-sant/mulsions-lipidiques-par-voie-intraveineuse-eli-intralipid-20
2017
false
false
false
Belgium
French
fat emulsions, intravenous
practice guideline
anesthetics, local
antidotes
Drug intoxication
poisoning
Lipophilicity
antidepressive agents, tricyclic
adrenergic beta-antagonists
antipsychotic agents
injections, intravenous
infusions, intravenous
Cardiotoxicity
---
https://pharmacomedicale.org/medicaments/par-specialites/item/42-2
2016
false
false
false
France
French
drug information
local anesthetic, nos
essential
anesthetics, local
local anesthesia, nos
---
http://www.cochrane.org/fr/CD004083
http://www.cochrane.org/fr/CD004083/comparaison-de-deux-formes-danesthesie-locale-pour-la-chirurgie-de-la-cataracte
2015
false
false
false
France
United Kingdom
Retrobulbar infiltration of local anesthetic (procedure)
Peribulbar infiltration of local anesthetic (procedure)
anesthetics, local
anesthesia, local
treatment outcome
anesthetics, local
anesthesia, local
review of literature
french abstract
cataract extraction
---
https://www.oiiq.org/sites/default/files/uploads/periodiques/Perspective/vol12no04/12-soins-chirurgicaux-acfa.pdf
2015
false
false
false
Canada
French
journal article
arthroplasty, replacement, knee
anesthetics, local
nerve block
anesthetics, local
---
http://www.cochrane.org/fr/CD010278/controle-de-la-douleur-laide-danesthesiques-locaux-pour-ameliorer-les-resultats-dune-chirurgie-de
2015
false
false
false
France
United Kingdom
French
french abstract
review of literature
arthroplasty, replacement, knee
arthroplasty, replacement, hip
arthroplasty, replacement
shoulder joint
treatment outcome
anesthesia, conduction
anesthesia, local
anesthetics, local
pain management
Arthroplasty, Replacement, Shoulder
---
https://www.cochrane.org/fr/CD009060/methodes-dadministration-intra-abdominale-danesthesique-local-chez-les-personnes-subissant-une-cholecystectomie-laparoscopique
2014
false
false
false
France
United Kingdom
french abstract
injections, intraperitoneal
anesthetics, local
cholecystectomy, laparoscopic
treatment outcome
review of literature
---
https://www.cochrane.org/fr/CD007049/infiltration-de-la-plaie-par-des-agents-anesthesiques-locaux-pour-la-cholecystectomie-laparoscopique-administration-dun-anesthesique-local-dans-la-plaie-chirurgicale-chez-les-personnes-subissant-une-cholecystectomie-laparoscopique
2014
false
false
false
France
United Kingdom
meta-analysis
french abstract
treatment outcome
pain, postoperative
anesthetics, local
cholecystectomy, laparoscopic
surgical wound, nos
---
http://www.cochrane.org/fr/CD007080/comparaison-dun-bloc-nerveux-du-membre-superieur-a-laide-dun-anesthesique-local-par-rapport-a-une-analgesie-aux-opiaces-dans-le-soulagement-de-la-douleur-apres-la-chirurgie-majeure-de-lepaule
2014
false
false
false
France
United Kingdom
review of literature
french abstract
pain, postoperative
brachial plexus
anesthetics, local
comparative study
treatment outcome
shoulder
shoulder joint
shoulder pain
nerve block
analgesics, opioid
---
http://www.cochrane.org/fr/CD010958/utilisation-topique-de-la-lidocaine-contre-les-douleurs-neuropathiques-chroniques-de-ladulte
2014
false
false
false
France
United Kingdom
French
french abstract
meta-analysis
treatment outcome
anesthetics, local
lidocaine
anesthetics, local
adult
neuralgia
chronic pain
lidocaine
---
http://sfar.org/?p=6664
http://sfar.org/techniques-analgesiques-locoregionales-et-douleur-chronique/
2013
true
France
French
headache
Cancer Pain Management
Cancer Pain
consensus
chronic pain
anesthesia, conduction
anesthetics, local
headache disorders
abdominal pain
pelvic pain
neuralgia
lower extremity
neoplasms
Cancer pain
---
https://www.sfetd-douleur.org/wp-content/uploads/2019/06/cahier_sfetd_n2_rfe_alr.pdf
2013
false
true
true
France
French
practice guideline
chronic pain
treatment outcome
anesthesia, conduction
anesthetics, local
analgesics, opioid
adrenal cortex hormones
ziconotide
headache disorders
pain management
neoplasms
Cancer Pain
Adrenocortical steroid therapy
corticosteroid therapy
Cancer Pain Management
Cancer Pain
omega-conotoxins
---
http://www.cochrane.org/fr/CD004081
2013
France
United Kingdom
French
french abstract
meta-analysis
lidocaine
postoperative complications
anesthetics, local
treatment outcome
pharyngitis
adult
intubation, intratracheal
anesthesia, general
---
http://www.cochrane.org/fr/CD007105
2013
false
United Kingdom
France
French
meta-analysis
chronic pain
pain, postoperative
anesthetics, local
anesthesia, conduction
treatment outcome
french abstract
---
http://www.cochrane.org/fr/CD005143
2013
United Kingdom
France
French
meta-analysis
cesarean section
bupivacaine
anesthetics, local
treatment outcome
anesthesia, spinal
french abstract
---
http://www.cochrane.org/fr/CD005622
2012
United Kingdom
France
French
review of literature
lidocaine
burns
pain management
treatment outcome
anesthetics, local
anesthetics, intravenous
pain
french abstract
---
http://www.cochrane.org/fr/CD007645
2012
United Kingdom
France
French
french abstract
meta-analysis
retinopathy of prematurity
infant, newborn
treatment outcome
ophthalmic solutions
anesthetics, local
eye pain
---
http://www.cochrane.org/fr/CD005657
2011
United Kingdom
France
French
Otitis media acute
Acute otitis media (disorder)
meta-analysis
earache
otitis media
acute disease
treatment outcome
anesthetics, local
french abstract
---
https://pgtmsite.files.wordpress.com/2024/01/dexmedetomidine_sedation_consciente_es_20111207.pdf
2011
Canada
drug information
Under No Sedation
adulthood
Conscious State
anesthetics, local
Regional Anesthesia Procedure
consciousness, nos
regional anesthesia, nos
Sedated
local anesthesia, nos
anesthesia, local
Sedation
Consciousness
Awareness
Legal Adult
conscious sedation
dexmedetomidine
Am Self-Conscious
sedation, nos
sedated state
Dexmedetomidine Hydrochloride
local anesthetic, nos
adult
Dexmedetomidine
Redundancy
Local Anesthesia Procedure
---
http://www.cochrane.org/fr/CD004598
2010
false
true
false
United Kingdom
France
treatment outcome
review of literature
french abstract
reflex sympathetic dystrophy
anesthetics, local
---
https://www.revmed.ch/RMS/2010/RMS-246/Anesthesie-locale-par-tumescence
2010
false
true
false
Switzerland
anesthetics, local
anesthetics, local
anesthetics, local
anesthetics, local
journal article
anesthesia, local
---
http://www.cochrane.org/fr/CD007710
2010
United Kingdom
France
French
meta-analysis
pain, postoperative
hysteroscopy
treatment outcome
ambulatory surgical procedures
anesthetics, local
analgesics
pain management
french abstract
---
https://ansm.sante.fr/uploads/2021/03/11/5a95c32110305ef7b385d03e8bec3708.pdf
2010
false
France
French
pain, intractable
adult
anesthetics, local
palliative care
sufentanil
fentanyl
drug therapy, combination
analgesics
ketamine
nitrous oxide
oxygen
methadone
midazolam
analgesics, opioid
propofol
anesthetics
administration, topical
injections
infusions, intravenous
anesthetics, inhalation
terminally ill
Off-Label use
practice guideline
guidelines for drug use
---
http://sfar.org/?p=6555
http://sfar.org/anesthesie-loco-regionale-en-pediatrie/
2010
true
France
French
anesthesia, conduction
child
anesthesia, conduction
infant
anesthetics, local
anesthesia, conduction
consensus
---
http://www.cochrane.org/fr/CD004223
2009
false
true
false
United Kingdom
France
perineum
pain
anesthetics, local
pregnancy
treatment outcome
review of literature
french abstract
---
https://healthycanadians.gc.ca/recall-alert-rappel-avis/hc-sc/2009/14044a-fra.php
https://healthycanadians.gc.ca/recall-alert-rappel-avis/hc-sc/2009/14544a-fra.php
2009
Canada
French
ointments
anesthetics, local
anesthetics, combined
pharmacovigilance note
popular works
---
https://www.paediatrieschweiz.ch/fr/evaluation-de-lefficacite-dun-gel-anesthesique-topique-let-pour-la-suture-des-plaies-cutanees-simples-chez-lenfant/
2008
false
Switzerland
French
pain measurement
child
suture techniques
anesthetics, local
journal article
---
https://minerva-ebp.be/fr/article/507
2008
false
minerva-ebm.be
Belgium
French
Otitis media acute
Acute otitis media (disorder)
otitis media
acute disease
child
lidocaine
anesthetics, local
earache
treatment outcome
critical appraisal or critical reading
---
http://www.cbip.be/Folia/Index.cfm?FoliaWelk=F35F03J
2008
Belgium
French
Dutch
anesthetics, local
administration, cutaneous
anesthetics, local
pharmacovigilance note
---
https://hemato.chu-limoges.fr/hematolim/Portals/0/Info_patient/soins%20de%20support/lutte%20contre%20la%20douleur/plaquette_anesthesiques_locaux_2010.pdf
2005
false
true
false
France
pain
popular works
anesthetics, local
---
https://www.cochrane.org/fr/CD003345/administration-systemique-dagents-anesthesiques-locaux-pour-soulager-la-douleur-neuropathique
2005
false
true
false
United Kingdom
France
treatment outcome
review of literature
french abstract
anesthetics, local
neuralgia
---
http://sfar.org/pratique-des-anesthesies-locales-et-locoregionales-par-des-medecins-non-specialises-en-anesthesie-reanimation/
2003
true
France
French
nerve block
resuscitation
anesthesia, local
anesthetics, local
administration, topical
anesthetics, local
anesthetics, local
anesthetics, local
lidocaine
lidocaine
prilocaine
administration, cutaneous
anesthesia, local
anesthesia, conduction
emergency treatment
leg injuries
arm injuries
facial injuries
hypnotics and sedatives
anesthesia, conduction
anesthesia, local
child
syncope, vasovagal
syncope, vasovagal
drug hypersensitivity
security measures
education, continuing
anesthesia, conduction
Evidence-Based medicine
consensus
---
