cocaine - CISMeF

Preferred Label : cocaine;

Obsolete resource : false;

MeSH definition : An alkaloid ester extracted from the leaves of plants including coca. It is a local anesthetic and vasoconstrictor and is clinically used for that purpose, particularly in the eye, ear, nose, and throat. It also has powerful central nervous system effects similar to the amphetamines and is a drug of abuse. Cocaine, like amphetamines, acts by multiple mechanisms on brain catecholaminergic neurons; the mechanism of its reinforcing effects is thought to involve inhibition of dopamine uptake.;

CISMeF synonym : 53-21-4 (Cocaine hydrochloride);

MeSH hyponym : cocaine hydrochloride; Hydrochloride, Cocaine; Cocaine HCl; HCl, Cocaine;

MeSH CAS label : 8-Azabicyclo(3.2.1)octane-2-carboxylic acid, 3-(benzoyloxy)-8-methyl-, methyl ester, (1R-(exo,exo))-;

MeSH Related Number : cocaine hydrochloride; 50-36-2 (Cocaine); 53-21-4 (HCl); XH8T8T6WZH;

Registry Number MeSH : 50-36-2;

Related CAS MeSH : XH8T8T6WZH (Cocaine hydrochloride);

MeSH annotation : cocaine derivatives COCAINE /analogs;CRACK COCAINE is available; cocaine addiction COCAINE-RELATED DISORDERS; cocaine derivatives COCAINE /analogs; CRACK COCAINE, COCAINE SMOKING and COCAINE-RELATED DISORDERS are available;

Wikipedia link : https://en.wikipedia.org/wiki/Cocaine;

Is substance : O;

UNII : I5Y540LHVR;

InChIKey : ZPUCINDJVBIVPJ-LJISPDSOSA-N;

Details

Origin ID

D003042;

UMLS CUI

C0009170;

ATC code(s)
- cocaine [ATC Code]
- cocaine [ATC Code]
- cocaine [ATC Code]
- cocaine [ATC Code]
Allowable qualifiers
- administration and dosage [MeSH Qualifier]
- adverse effects [MeSH Qualifier]
- agonists [MeSH Qualifier]
- analogs and derivatives [MeSH Qualifier]
- analysis [MeSH Qualifier]
- antagonists and inhibitors [MeSH Qualifier]
- biosynthesis [MeSH Qualifier]
- blood [MeSH Qualifier]
- cerebrospinal fluid [MeSH Qualifier]
- chemical synthesis [MeSH Qualifier]
- chemistry [MeSH Qualifier]
- classification [MeSH Qualifier]
- contraindications [MeSH Qualifier]
- economics [MeSH Qualifier]
- genetics [MeSH Qualifier]
- history [MeSH Qualifier]
- immunology [MeSH Qualifier]
- isolation and purification [MeSH Qualifier]
- metabolism [MeSH Qualifier]
- pharmacokinetics [MeSH Qualifier]
- pharmacology [MeSH Qualifier]
- poisoning [MeSH Qualifier]
- radiation effects [MeSH Qualifier]
- standards [MeSH Qualifier]
- supply and distribution [MeSH Qualifier]
- therapeutic use [MeSH Qualifier]
- toxicity [MeSH Qualifier]
- urine [MeSH Qualifier]
Automatic exact mappings (from CISMeF team)
- Benzoylmethylecgonine (substance) [SNOMED CT concept]
- Cocaine [HPMULTI term]
- Cocaine [ICHI section]
- Cocaine Hydrochloride [NCIt concept]
- Cocaine hydrochloride [Substance BNPC]
- Cocaine hydrochloride (substance) [SNOMED CT concept]
- Cocaine-induced acrocyanosis and livedo reticularis (disorder) [SNOMED CT concept]
- Narcotic drugs [UNESCO concept]
- Poisoning by and exposure to narcotics and psychodysleptics [hallucinogens], not elsewhere classified, undetermined intent [ICD-10 category (who)]
- Poisoning by, adverse effect of and underdosing of cocaine [ICD-10 Sub-category]
- benzoylmethylecgonine [SNOMED Notion]
- cocaine hydrochloride [SNOMED Notion]
- white [Radlex concept]
False automatic mappings
- Accidental poisoning by and exposure to narcotics and psychodysleptics [hallucinogens], not elsewhere classified [ICD-10 category (who)]
- Cocaine [ICD-10 Sub-category (who)]
- Intentional self-poisoning by and exposure to narcotics and psychodysleptics [hallucinogens], not elsewhere classified [ICD-10 category (who)]
- Poisoning by, adverse effect of and underdosing of cocaine [ICD-10 Sub-category]
Indexing information
- 3-(4-(4-cyclohexylpiperazin-1-yl)butyl)benzo(d)thiazole-2(3H)-thione [MeSH Supplementary Concept]
- cocaine receptor [MeSH Supplementary Concept]
Manual BTNT mappings - CISMeF
- Cocaine topical anesthetic [ICD-11 Extension code]
Pharmacological action(s)
- anesthetics, local [MeSH Descriptor]
- dopamine uptake inhibitors [MeSH Descriptor]
- vasoconstrictor agents [MeSH Descriptor]
Record concept(s)
- cocaine [MeSH concept]
- cocaine hydrochloride [MeSH concept]
Related MeSH Supplementary Concept(s)
- (1R-(exo,exo))-3-(4-fluorophenyl)-8-methyl-8- azabicyclo(3.2.1)octane-2-carboxylic acid, methyl ester [MeSH Supplementary Concept]
- (4'-isopropenyl-phenyl)nortropane-2-beta-carboxylic acid methylester [MeSH Supplementary Concept]
- 2'-fluoroethyl 8-methyl-3-(4-chlorophenyl)-8-azabicyclo(3.2.1)octane-2-carboxylate [MeSH Supplementary Concept]
- 2'-fluoroethyl 8-methyl-3-(4-methylphenyl)-8-azabicyclo(3.2.1)octane-2-carboxylate [MeSH Supplementary Concept]
- 2,3-dehydrococaine [MeSH Supplementary Concept]
- 2-carbomethoxy-3-(3'-iodophenyl)tropane [MeSH Supplementary Concept]
- 2-fluoroethyl 8-(3-iodoprop-2-en-1-yl)-3-(4-iodophenyl)-8-azabicyclo(3.2.1)octane-2-carboxylate [MeSH Supplementary Concept]
- 2-propanoyl-3-(2-naphthyl)-tropane [MeSH Supplementary Concept]
- 2-propanoyl-3-(4-tolyl)tropane [MeSH Supplementary Concept]
- 2beta-carbomethoxy-3beta-(4-iodophenyl)tropane [MeSH Supplementary Concept]
- 3'-hydroxy-4'-methoxycocaine [MeSH Supplementary Concept]
- 3'-hydroxycocaine [MeSH Supplementary Concept]
- 3-((2'-hydroxy-4'-iodobenzoyl)oxy)-8-methyl-8-azabicyclo(3.2.1)octane-2-carboxylic acid isopropyl ester [MeSH Supplementary Concept]
- 3-(3-fluoro-4-methylphenyl)nortropane-2-carboxylic acid methyl ester [MeSH Supplementary Concept]
- 3-(4'-azido-3'-iodobiphenyl-4-yl)-8-methyl-8-azabicyclo(3.2.1)octane-2-carboxylic acid methyl ester [MeSH Supplementary Concept]
- 3-(4-chlorophenyl)tropane-2-carboxylic acid methyl ester [MeSH Supplementary Concept]
- 3-(4-ethyl-3-iodophenyl)nortropane-2-carboxylic acid methyl ester [MeSH Supplementary Concept]
- 3-(4-fluorobenzoyloxy)tropane [MeSH Supplementary Concept]
- 3-(4-iodophenyl)tropan-2beta-carboxylic acid phenyl ester [MeSH Supplementary Concept]
- 3-beta-(4'-n-propyl)nortropane-2-beta-carboxylic acid methyl ester [MeSH Supplementary Concept]
- 3-hydroxybenzoylecgonine [MeSH Supplementary Concept]
- 3-iodo-4-azidococaine [MeSH Supplementary Concept]
- 3beta-(2-fluoromethylphenyl)tropane-2beta-carboxylic acid methyl ester [MeSH Supplementary Concept]
- 3beta-(4-fluoromethylphenyl)tropane-2beta-carboxylic acid methyl ester [MeSH Supplementary Concept]
- 4'-fluorococaine [MeSH Supplementary Concept]
- 4'-hydroxy-3'-methoxycocaine [MeSH Supplementary Concept]
- 4'-hydroxycocaine [MeSH Supplementary Concept]
- 4'-iodococaine [MeSH Supplementary Concept]
- 4'-isopropylnortropane-2-beta-carboxylic acid methyl ester [MeSH Supplementary Concept]
- 4'-phenylcocaine [MeSH Supplementary Concept]
- 4,5,6,7,8,9,10,11,13,17a,18,19,20,21,22,22a-hexadecahydro-23-methyl-14,17-etheno-19,22-imino-1H-cyclohept(c)(1,9)oxaazacyclononadecine-3,12-dione [MeSH Supplementary Concept]
- 4-hydroxybenzoylecgonine [MeSH Supplementary Concept]
- 5,6,7,8,10,14a,15,16,17,18,19,19a-dodecahydro-20-methyl-11,14-etheno-16,19-iminocyclohept(c)(1,9)oxaazacyclohexadecine-3,9(1H,4H)-dione [MeSH Supplementary Concept]
- 6-(3-(benzoyloxy)-8-methyl-8-azabicyclo(3.2.1)octane-2-carboxoamido)hexanoic acid [MeSH Supplementary Concept]
- 6-methyl-3-(4-iodo)phenyltropane-2-carboxylic acid methyl ester [MeSH Supplementary Concept]
- 7-methyl-3-(4-iodo)phenyltropane-2-carboxylic acid methyl ester [MeSH Supplementary Concept]
- 8-((E)-4-fluoro-but-2-enyl)-3beta-p-tolyl-8-aza-bicyclo(3.2.1)octane-2beta-carboxylic acid methyl ester [MeSH Supplementary Concept]
- 8-(2-fluoroethyl)-3-(4-iodophenyl)-8-azabicyclo(3.2.1)octane-2-carboxylic acid methyl ester [MeSH Supplementary Concept]
- 8-hydroxynorcocaine [MeSH Supplementary Concept]
- 8-methyl-3-(4-methylphenyl)tropane--2-carboxylic acid N-methyl-N-(4-nitrobenzo-2-oxa-1,3-diazol-7-yl)ethanolamine ester [MeSH Supplementary Concept]
- 8-oxanorcocaine [MeSH Supplementary Concept]
- N-(2-fluoroethyl)-3beta-(4-iodophenyl)-8-methyl-8-azabicyclo(3.2.1)octane-2alpha-carboxamide [MeSH Supplementary Concept]
- N-allylnorcocaine [MeSH Supplementary Concept]
- N-benzoylnormethylecgonine [MeSH Supplementary Concept]
- N-formylnorcocaine [MeSH Supplementary Concept]
- N-iodoallyl-2-carbomethoxy-3-(4-fluorophenyl)tropane [MeSH Supplementary Concept]
- N-nor-3-(4'-ethylphenyl)tropane-2-carboxylic acid methyl ester [MeSH Supplementary Concept]
- N-nor-3-(4'-iodophenyl)tropane-2-carboxylic acid methyl ester [MeSH Supplementary Concept]
- RTI 117 [MeSH Supplementary Concept]
- RTI 121 [MeSH Supplementary Concept]
- RTI 130 [MeSH Supplementary Concept]
- RTI 352 [MeSH Supplementary Concept]
- RTI 82 [MeSH Supplementary Concept]
- RTI-113 [MeSH Supplementary Concept]
- RTI-COC 32 [MeSH Supplementary Concept]
- SNC-rCTB vaccine [MeSH Supplementary Concept]
- TEC solution [MeSH Supplementary Concept]
- aluminum hydroxide, cimetidine, cocaine, hydroxyzine, morphine drug combination [MeSH Supplementary Concept]
- anhydroecgonine methyl ester [MeSH Supplementary Concept]
- anhydroecgonine methyl ester N-oxide [MeSH Supplementary Concept]
- benzoylecgonine [MeSH Supplementary Concept]
- benzoylecgonine isopropyl ester [MeSH Supplementary Concept]
- benzoylnorecgonine [MeSH Supplementary Concept]
- bonain's liquid [MeSH Supplementary Concept]
- cinnamoylcocaine [MeSH Supplementary Concept]
- cocaethylene [MeSH Supplementary Concept]
- cocaine N-oxide [MeSH Supplementary Concept]
- cocaine benzoyl thioester [MeSH Supplementary Concept]
- cocaine methiodide [MeSH Supplementary Concept]
- cocaine, dipicrylaminate drug combination [MeSH Supplementary Concept]
- dichloropane [MeSH Supplementary Concept]
- difluoropine [MeSH Supplementary Concept]
- ecgonidine [MeSH Supplementary Concept]
- ecgonine [MeSH Supplementary Concept]
- ecgonine methyl ester [MeSH Supplementary Concept]
- ethyl ecgonine [MeSH Supplementary Concept]
- methyl 3-benzoyloxy-7-methoxy-8-methyl-8-azabicyclo(3.2.1)octane-2-carboxylate [MeSH Supplementary Concept]
- methyl-8-((2-(fluoromethyl)cyclopropyl)methyl)-3-phenyl-8-azabicyclo(3.2.1)octane-2-carboxylate [MeSH Supplementary Concept]
- noranhydroecgonine [MeSH Supplementary Concept]
- norcocaethylene [MeSH Supplementary Concept]
- norcocaine [MeSH Supplementary Concept]
- norcocaine nitroxide [MeSH Supplementary Concept]
- nortropacocaine [MeSH Supplementary Concept]
- pseudococaine [MeSH Supplementary Concept]
- trimethylstannyl-(2-carbomethoxy-3-(4-phenyl)tropane) [MeSH Supplementary Concept]
- tropacocaine [MeSH Supplementary Concept]
- troparil [MeSH Supplementary Concept]
- tropoxene [MeSH Supplementary Concept]
See also
- Cocainum Hydrochloricum [DeCS]
See also (suggested by CISMeF)
- Cocaine Smoking [MeSH Descriptor]
- cocaine-related disorders [MeSH Descriptor]
- narcotics [MeSH Descriptor]
See also inter- (CISMeF)
- Cocaine Measurement [NCIt concept]
- Cocaine panel [LOINC component]
- Product containing cocaine (medicinal product) [SNOMED CT concept]
Semantic type(s)
- Hazardous or Poisonous Substance [UMLS semantic type]
- Organic Chemical [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
UMLS correspondences (same concept)
- Benzoylmethylecgonine (substance) [SNOMED CT concept]
- Cocaine [ICD-10 Sub-category (who)]
- Cocaine [NCIt concept]
- Cocaine [LOINC component]
- Cocaine (substance) [SNOMED CT concept]
- Product containing cocaine (medicinal product) [SNOMED CT concept]
- cocaine [ATC Code]
- cocaine [ATC Code]
- cocaine [ATC Code]
- cocaine [ATC Code]
- cocaine [SNOMED Notion]
- cocaine [MedlinePlus Topic]
Validated automatic mappings to BTNT
- Cocaine hydrochloride [SMS substance]
- cocaine [ATC Code]
- cocaine [ATC Code]
- cocaine [ATC Code]
- cocaine [ATC Code]

Keyword's position in hierarchy(ies) :

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