Preferred Label : Neoantigen-HSP70 Peptide Cancer Vaccine AGEN2017;
NCIt synonyms : AutoSynVax Vaccine; ASV AGEN2017; AutoSynVax AGEN2017; Autologous Cancer Vaccine AGEN2017; Neoantigen Vaccine AGEN2017;
NCIt definition : A proprietary, personalized autologous synthetic cancer vaccine composed of patient-specific
synthetic cancer neo-epitopes complexed with heat shock protein 70 (HSP 70; HSP70),
with potential immunostimulating and antineoplastic activities. Upon administration
of the neoantigen-HSP70 peptide cancer vaccine AGEN2017, the HSPs present the neoantigens
to antigen presenting cells (APCs) and help elicit a potent neoantigen-specific T-cell-based
anti-tumor immune response, thereby killing the neoantigen-expressing cancer cells.
HSP70 is able to the transport the neo-epitopes, activate APCs and enhance the T-cell-mediated
immune response.;
Drug name : AutoSynVax; ASV;
Molecule name : AGEN-2017; AGEN 2017;
NCI Metathesaurus CUI : CL523816;
Origin ID : C135018;
UMLS CUI : C5206915;
Semantic type(s)
- chemical_or_drug_has_mechanism_of_action
- concept_is_in_subset
https://www.has-sante.fr/jcms/p_3474308/en/aircurve-11-asv-pacewave
2023
France
health technology assessment
SRC wt Allele
ventilation
ventilation, nos
Drug Delivery System
Enslavement
Ventilation
Neoantigen-HSP70 Peptide Cancer Vaccine AGEN2017
Theophylline
Asunaprevir
Device System
Drug Delivery System Category
Eleven
Loss of Chromosome 11
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