" /> Mucin-16 - CISMeF





Preferred Label : Mucin-16;

NCIt synonyms : Ovarian Cancer-Related Tumor Marker CA125; CA-125; Ovarian Carcinoma Antigen CA125; Mucin 16; MUC16;

NCIt definition : Mucin-16 (22152 aa, 2353 kDa) is encoded by the human MUC16 gene. This protein may be involved in both cellular adhesion and the lubrication of mucosal surfaces.;

NCIt note : Mucin-16 is a glycoprotein that is synthesized with a single transmembrane domain, and can be proteolytically released from the membrane after intracellular phosphorylation occurs. This protein has been identified as the CA-125 ovarian cancer antigen, which is the basis for a widely used serum assay for the monitoring of patients with ovarian epithelial cancer. This marker cannot detect early ovarian cancer and is not specific enough to be used for population screening. (SwissProt);

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15/05/2024


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