Nuclear Factor Erythroid 2-Related Factor 2

Preferred Label : Nuclear Factor Erythroid 2-Related Factor 2;

NCIt synonyms : NF-E2-Related Factor 2; NFE2-Related Factor 2; HEBP1; Nuclear Factor, Erythroid Derived 2, Like 2; NFE2L2 Protein; NFE2L2; NRF2;

NCIt definition : Nuclear factor erythroid 2-related factor 2 protein (605 aa, 68 kDa) is encoded by the human NFE2L2 gene. This transcription factor is involved in cellular antioxidant defense and beta-globin activity modulation.;

Details

Origin ID

C54255;

UMLS CUI

C1565078;

OMIM relation
- Nuclear factor erythroid 2-like 2 [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Biologically Active Substance [UMLS semantic type]
UMLS correspondences (same concept)
- NFE2L2 protein, human [MeSH Supplementary Concept]
- NFE2L2 protein, human [MeSH concept]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
- NCIt COVID-19 Clinical Terminology [NCIt concept]
- NCIt COVID-19 Terminology [NCIt concept]
gene_encodes_gene_product
- NFE2L2 Gene [NCIt concept]
- Regulatory Gene [NCIt concept]
- Transcription Factor Gene [NCIt concept]
- Transcription Regulation Gene [NCIt concept]
gene_product_has_associated_anatomy
- Nucleus [NCIt concept]
gene_product_has_biochemical_function
- DNA Binding Protein [NCIt concept]
gene_product_has_structural_domain_or_motif
- bZIP Domain [NCIt concept]
gene_product_is_element_in_pathway
- Oxidative Stress Pathway [NCIt concept]
gene_product_plays_role_in_biological_process
- DNA Binding [NCIt concept]
- Oxidative Stress [NCIt concept]
- Transcriptional Regulation [NCIt concept]
is_target
- Dimethyl Fumarate [NCIt concept]
- NFE2L2/KEAP1/CUL3 Mutant-targeting Agent MGY825 [NCIt concept]

Keyword's position in hierarchy(ies) :

You can consult :

recommendations
documents concerning education
documents for patients