RARA wt Allele

Preferred Label : RARA wt Allele;

NCIt synonyms : RAR; NR1B1; Retinoic Acid Receptor Alpha wt Allele; RARA;

NCIt definition : Human RARA wild-type allele is located within 17q21 and is approximately 48 kb in length. This allele, which encodes retinoic acid receptor alpha protein, is involved in myeloid-specific transcription and retinoic acid receptor signal transduction.;

GenBank Accession Number : NM_000964;

Details

Origin ID

C51711;

UMLS CUI

C1705627;

OMIM relation
- Retinoic acid receptor, alpha [OMIM gene]
Semantic type(s)
- Gene or Genome [UMLS semantic type]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_found_in_organism
- Human [NCIt concept]
gene_in_chromosomal_location
- 17q12 [NCIt concept]
gene_involved_in_pathogenesis_of_disease
- Acute Myeloid Leukemia with a Variant RARA Rearrangement [NCIt concept]
- Acute Promyelocytic Leukemia with t(15;17)(q24.1;q21.2); PML-RARA [NCIt concept]
gene_is_element_in_pathway
- Acute Myeloid Leukemia Pathway [NCIt concept]
- CARM1 Transcription Regulation Pathway [NCIt concept]
- Chromatin Remodeling Complex and Coactivator Pathway [NCIt concept]
- Map Kinase Inactivation of SMRT Corepressor Pathway [NCIt concept]
- RAR and RXR Degradation Pathway [NCIt concept]
- Retinoic Acid Receptor Family-Mediated Signaling Pathway [NCIt concept]
gene_plays_role_in_process
- Cell Differentiation Process [NCIt concept]
- Cell Proliferation [NCIt concept]
- DNA Binding [NCIt concept]
- Homeostatic Process [NCIt concept]
- Ligand Binding [NCIt concept]
- Maturation [NCIt concept]
- Pattern Formation [NCIt concept]
- Receptor Signaling [NCIt concept]
- Retinoic Acid Binding [NCIt concept]
- Signal Transduction [NCIt concept]
- Transcriptional Activation [NCIt concept]
- Transcriptional Regulation [NCIt concept]

Keyword's position in hierarchy(ies) :

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