ITGB2 wt Allele

Preferred Label : ITGB2 wt Allele;

NCIt synonyms : CD18; LAD; LFA-1; LCAMB; MF17; Integrin, Beta-2 Gene; Integrin Beta Chain, Beta 2 Gene; MAC-1; MFI7; Integrin, Beta 2 (Complement Component 3 Receptor 3 and 4 Subunit) Gene; Integrin, Beta 2 (Antigen CD18 (p95), Lymphocyte Function-Associated Antigen 1; Macrophage Antigen 1 (MAC-1) Beta Subunit) Gene; Complement Component 3 Receptor 3 and 4 Subunit Gene; Cell Surface Adhesion Glycoprotein (LFA-1/CR3/P150,959 Beta Subunit Precursor) Gene; Integrin Subunit Beta 2 wt Allele;

NCIt definition : Human ITGB2 wild-type allele is located in the vicinity of 21q22.3 and is approximately 35 kb in length. This allele, which encodes integrin beta-2 protein, is involved in cellular adhesion as well as cell-surface mediated signal transduction.;

GenBank Accession Number : NM_000211;

Details

Origin ID

C51172;

UMLS CUI

C1706333;

Automatic exact mappings (from CISMeF team)
- Anterior interventricular branch of left coronary artery [FMA entity]
- CD18 [LOINC component]
- CD18 Antigens [MeSH Descriptor]
- CD18 cells [LOINC component]
- Dihydrolipoamide dehydrogenase [OMIM gene]
- Entire anterior descending branch of left coronary artery (body structure) [SNOMED CT concept]
- Integrin, beta-2 [OMIM gene]
- Leukocyte adhesion deficiency [ICD-11 More detail]
- Leukocyte adhesion deficiency [ORDO Disease]
- Leukocyte adhesion deficiency, type I [OMIM Phenotype]
- diffuse axonal injury [MeSH Descriptor]
- dihydrolipoamide dehydrogenase [MeSH Descriptor]
- dihydrolipoamide dehydrogenase [ORDO Gene]
- integrin subunit alpha M [ORDO Gene]
- integrin subunit beta 2 [ORDO Gene]
- left anterior descending artery [Radlex concept]
- leukocyte-adhesion deficiency syndrome [MeSH Descriptor]
- lymphocyte Function-Associated Antigen-1 [MeSH Descriptor]
- lymphocyte Function-Associated Antigen-1 [MeSH concept]
False automatic mappings
- LADS [IUPAC Term]
- dispensation assistance software [EFMI term]
OMIM relation
- Integrin, beta-2 [OMIM gene]
Semantic type(s)
- Gene or Genome [UMLS semantic type]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_associated_with_disease
- Leukocyte Adhesion Deficiency [NCIt concept]
gene_found_in_organism
- Human [NCIt concept]
gene_has_physical_location
- 21: 45165232-45130314 [NCIt concept]
gene_in_chromosomal_location
- 21q22.3 [NCIt concept]
gene_is_element_in_pathway
- Actin Cytoskeleton Regulation Pathway [NCIt concept]
- AlphaM/Beta2 Integrin Signaling Pathway [NCIt concept]
- Amoebiasis Pathway [NCIt concept]
- CXCR3-Mediated Signaling Pathway [NCIt concept]
- Cell Adhesion Molecule Signaling Pathway [NCIt concept]
- HIF-1-Alpha Transcription Factor Pathway [NCIt concept]
- Leishmaniasis Infection Pathway [NCIt concept]
- Leukocyte Transendothelial Migration Pathway [NCIt concept]
- Malaria Pathway [NCIt concept]
- Natural Killer Cell-Mediated Cytotoxicity Pathway [NCIt concept]
- Phagocytosis Pathway [NCIt concept]
- Viral Myocarditis Pathway [NCIt concept]
gene_plays_role_in_process
- Cell Adhesion Process [NCIt concept]
- Cell-Cell Adhesion Process [NCIt concept]
- Heterodimerization [NCIt concept]
- Ligand Binding [NCIt concept]
- Receptor Signaling [NCIt concept]
- Signal Transduction [NCIt concept]

Keyword's position in hierarchy(ies) :

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