NCIt synonyms : MCAF; MCP-1; MCP1; HC11; GDCF-2; Chemokine, CC Motif, Ligand 2 Gene; SMC-CF; SCYA2; Chemokine (C-C Motif) Ligand 2 wt Allele; MGC9434; Small Inducible Cytokine Subfamily A, Member 2 Gene; Small Inducible Cytokine Subfamily A (Cys-Cys), Member 2 Gene; Small Inducible Cytokine A2 (Monocyte Chemotactic Protein 1, Homologous to Mouse Sig-Je)
Gene; Homologous to Mouse Sig-Je Gene; HSMCR30;
NCIt definition : Human CCL2 wild-type allele is located within 17q11.2-q12 and is approximately 2 kb
in length. This allele, which encodes C-C motif chemokine 2 protein, is involved in
the mediation of immune cell chemotaxis during tissue injury.;
NCIt note : Human CCL2 Gene encodes a chemotactic chemokine for monocytes and basophils, but not
neutrophils or eosinophils, that is produced by monocytic and lymphocytic leukocytes
and by fibroblasts during tissue injury that binds to chemokine receptors CCR2 and
CCR4.;