MDM2 Gene Amplification

Preferred Label : MDM2 Gene Amplification;

NCIt synonyms : Mouse Double Minute 2 Gene Amplification; MDM2 Proto-Oncogene Gene Amplification; Double Minute 2 Homolog Gene Amplification; HDMX Gene Amplification; hdm2 Gene Amplification; MDM2 Proto-Oncogene, E3 Ubiquitin Protein Ligase Gene Amplification; Mouse Double Minute 2 Homolog Gene Amplification; ACTFS Gene Amplification;

NCIt definition : A molecular genetic abnormality indicating the presence of multiple copies of the MDM2 gene.;

Details

Origin ID

C36681;

UMLS CUI

C1518116;

Automatic exact mappings (from CISMeF team)
- MDM2 gene amplification [LOINC component]
Molecular abnormality of diseases
- Adult Brain Glioblastoma [NCIt concept]
- Adult Brain Stem Gliosarcoma [NCIt concept]
- Adult Giant Cell Glioblastoma [NCIt concept]
- Adult Glioblastoma [NCIt concept]
- Adult Gliosarcoma [NCIt concept]
- Adult Spinal Cord Glioblastoma [NCIt concept]
- Advanced Dedifferentiated Liposarcoma [NCIt concept]
- Atypical Lipomatous Tumor/Well Differentiated Liposarcoma [NCIt concept]
- Atypical Lipomatous Tumor/Well Differentiated Liposarcoma of Deep Soft Tissue [NCIt concept]
- Brain Glioblastoma [NCIt concept]
- Brain Stem Glioblastoma [NCIt concept]
- Cerebellar Glioblastoma [NCIt concept]
- Cerebral Glioblastoma [NCIt concept]
- Childhood Brain Glioblastoma [NCIt concept]
- Childhood Brain Stem Gliosarcoma [NCIt concept]
- Childhood Gliosarcoma [NCIt concept]
- Dedifferentiated Liposarcoma [NCIt concept]
- Diencephalic Glioblastoma [NCIt concept]
- Gliosarcoma [NCIt concept]
- Inflammatory Atypical Lipomatous Tumor/Well Differentiated Liposarcoma [NCIt concept]
- Infratentorial Glioblastoma [NCIt concept]
- Intimal Sarcoma [NCIt concept]
- Juvenile Trabecular Ossifying Fibroma [NCIt concept]
- Lipoma-Like Atypical Lipomatous Tumor/Well Differentiated Liposarcoma [NCIt concept]
- Locally Advanced Dedifferentiated Liposarcoma [NCIt concept]
- Low Grade Central Osteosarcoma [NCIt concept]
- Malignant Testicular Leydig Cell Tumor [NCIt concept]
- Metastatic Dedifferentiated Liposarcoma [NCIt concept]
- Pulmonary Artery Intimal Sarcoma [NCIt concept]
- Recurrent Brain Glioblastoma [NCIt concept]
- Recurrent Childhood Gliosarcoma [NCIt concept]
- Recurrent Dedifferentiated Liposarcoma [NCIt concept]
- Recurrent Gliosarcoma [NCIt concept]
- Recurrent Supratentorial Glioblastoma [NCIt concept]
- Refractory Dedifferentiated Liposarcoma [NCIt concept]
- Refractory Gliosarcoma [NCIt concept]
- Resectable Dedifferentiated Liposarcoma [NCIt concept]
- Sclerosing Atypical Lipomatous Tumor/Well Differentiated Liposarcoma [NCIt concept]
- Skin Atypical Lipomatous Tumor/Well Differentiated Liposarcoma [NCIt concept]
- Superficial Atypical Lipomatous Tumor/Well Differentiated Liposarcoma [NCIt concept]
- Supratentorial Glioblastoma [NCIt concept]
- Supratentorial Gliosarcoma [NCIt concept]
- Unresectable Dedifferentiated Liposarcoma [NCIt concept]
Semantic type(s)
- Cell or Molecular Dysfunction [UMLS semantic type]
UMLS correspondences (same concept)
- MDM2 gene amplification [LOINC component]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
is_abnormality_of_gene
- MDM2 Gene [NCIt concept]
- MDM2 SNP309 Allele [NCIt concept]
- MDM2 wt Allele [NCIt concept]
is_not_molecular_abnormality_of_disease
- Myxoid Pleomorphic Liposarcoma [NCIt concept]
molecular_abnormality_involves_gene
- MDM2 Gene [NCIt concept]

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